Evidence map›Paper›PMID 38167215›Full record

ArticleThyroid research2024

Radiofrequency ablation for thyroid nodules in Ecuador: a cross-sectional study.

Cristhian Garcia, Paola Solis-Pazmino, Eddy P Lincango, Andrea S Cho-Tana, Luis Figueroa, Oscar J Ponce, Juan P Brito, Erivelto Volpi

Open access · goldAbstract read
In one paragraph

Article in Thyroid research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Cristhian Garcia *Instituto de Tiroides y Enfermedades de Cabeza y Cuello (ITECC), Quito, Ecuador.
Paola Solis-Pazmino *Instituto de Tiroides y Enfermedades de Cabeza y Cuello (ITECC), Quito, Ecuador. paosolpaz18@gmail.com.ORCID http://orcid.org/0000-0003-1725-232X
Eddy P LincangoInstituto de Tiroides y Enfermedades de Cabeza y Cuello (ITECC), Quito, Ecuador.
Andrea S Cho-TanaInstituto de Tiroides y Enfermedades de Cabeza y Cuello (ITECC), Quito, Ecuador.
Luis FigueroaInstituto de Tiroides y Enfermedades de Cabeza y Cuello (ITECC), Quito, Ecuador.
Oscar J PonceInstituto de Tiroides y Enfermedades de Cabeza y Cuello (ITECC), Quito, Ecuador.
Juan P BritoDivision of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, MN, 55905, USA.
Erivelto VolpiOncology Center, Oswaldo Cruz German Hospital, Sao Paulo, Brazil.
Hospital Alemão Oswaldo Cruz · BRMayo Clinic · USMayo Clinic in Arizona · USMayo Clinic in Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo describe the demographic characteristics and clinical outcomes following the first cohort of patients with Bening Thyroid Nodule (BTN) and (Papillary Thyroid Microcarcinoma) (PTMC) treated with Radiofrequency Ablation (RFA)in Ecuador.

methodsSingle-center, cross-sectional study. We included adults undergoing RFA for BTN and PTMC between July 2019 and May 2022. Descriptive statistics and the Wilcoxon signed-rank test were used to compare some pre- and post-intervention outcomes.

resultsWe included 44 patients with 36 BTNs and eight PTMCs. The median age was 45.80 years (IQR 16-79 years), and most patients had normal thyroid function (72.72%). The median follow-up time was 7.80 months (IQR1.0-34.0). Nodules were primarily solid (43.21%) or predominantly solid (56.81%). The pre-RFA median volume in the benign lesions group was 10.30 ml (IQR 1.86-18.97). After ablation, the 1-month, 3-month, 6-month, and 12-month median volumes were 6.90 (IQR 0.48-10.15; p < 0.01) mL, 5.72 (IQR 0.77-7.25; p = 0.045); 0.98 (IQR 0.25-3.64; p < 0.01), and 0.11 (IQR 0.07-11.26; p = 0.026), respectively. The volume rate reduction was 47.20%, 72.20%, 74.00%, and 96.20% at 1, 3, 6, and 12-month follow-ups, respectively. The pre-RFA median volume in the PTMC group was 0.25 ml (IQR 0.19-0.48). After ablation, the 1-month, 3-month, and 6-month mean volumes were 0.19 (range 0.12-0.31; p = 0.120) mL, 0.10 (IQR 0.05-0.15; p = 0.13), and 0.01 (IQR 0.005-0.04; p = 0.364), respectively.

conclusionsIn this first report from Ecuador, we found that RFA may be a feasible alternative for treating benign and malignant thyroid nodules in the short term. Long-term data are needed to evaluate oncologic outcomes in PTMC patients.

Indexed as

Benign thyroid noduleMicrocarcinomaRadiofrequency

Identifiers

PMID38167215
PMCPMC10763036
OpenAlexW4390521539

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.