ArticleBMC public health2024
Exploring the connection between caffeine intake and constipation: a cross-sectional study using national health and nutrition examination survey data.
Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- The Effectiveness of Caffeine in Reducing Constipation in Adults: A Systematic Review.International urogynecology journal · 2025Pooled it
- Association between blood lead levels and constipation in adults: insights from NHANES data (2005-2010).BMC gastroenterology · 2025Article
- Association between the dietary index for gut microbiota and constipation in American adults.Nutrition journal · 2025Article
- The relationship of cardiometabolic index with bowel movement frequency: an NHANES-based cross-sectional analysis.Lipids in health and disease · 2025Article
- Association of constipation with suicidal ideation among US adults and the partial mediating role of depression.Scientific reports · 2025Article
- Association of anxiety status and anxiety duration with constipation in adult Americans: a cross-sectional study using data from the NHANES 2007-2010.BMC gastroenterology · 2025Article
- Exploring the association between dietary caffeine and chronic musculoskeletal pain: a cross-sectional analysis of NHANES.Frontiers in nutrition · 2025Article
- Association Between Caffeine Intake and Bowel Habits and Inflammatory Bowel Disease: A Population-Based Study.Journal of multidisciplinary healthcare · 2025Article
- Self-Reported Gastrointestinal Symptoms Associated with NSAIDs and Caffeine Consumption in a Jordanian Subpopulation.Medicina (Kaunas, Lithuania) · 2024Article
- Associations between the oxidative balance score and constipation: a cross-sectional study of the NHANES, 2005-2010.BMC public health · 2024Article
- Exploring the association between cardiovascular health and bowel health.Scientific reports · 2024Article
- Exploring the association between caffeine intake and benign prostatic hyperplasia: results from the NHANES 2005-2008.Frontiers in nutrition · 2024Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCaffeine has been reported to increase gastrointestinal motility and change intestinal microbiota. Constipation may be caused by colonic motor dysfunction and colonic microbiomeis disturbances. In this study, we aimed to explore the association between caffeine intake and constipation.
methodsThis was a cross-sectional study based on the National Health and Nutrition Examination Survey (NHANES). Caffeine intake was assessed using 24-h dietary recall method, and constipation was defined based on stool consistency or stool frequency. Logistic regression analysis was used to assess the association between caffeine intake and constipation, and results were expressed as odds ratio (OR) with 95% confidence intervals (95%CI). Subgroup analysis was performed based on age.
resultsA total of 13,816 participants were finally included for analysis. After adjusting potential confounders, high intake of caffeine was found to be associated with the low odds of constipation (Q3: OR = 0.60, 95%CI: 0.49-0.74; Q4: OR = 0.77, 95%CI: 0.59-0.99; Q5: OR = 0.72, 95%CI: 0.56-0.92). The similar association was found in young people and middle-age people (P < 0.05).
conclusionHigh caffeine intake was associated with the low odds of constipation. Our finding indicated that individuals should develop consciousness and habit of consuming caffeinated foods and drinks to prevent and relief the constipation.
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