Observational studyBMC surgery2024
Blood loss quantification during major abdominal surgery: prospective observational cohort study.
Observational study in BMC surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05316649 (Blood Loss Quantification During Major Abdominal Surgery), which is not on this map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Blood Loss Quantification During Major Abdominal Surgery: Study Protocol for a Prospective Cohort Trial.
Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- Definition, analysis, reporting, and interpretation of perioperative bleeding in randomized controlled trials: a methodological systematic review.Perioperative medicine (London, England) · 2026Review
- Perioperative blood loss in robotic urologic surgery: a retrospective evaluation of estimation methods.Journal of robotic surgery · 2026Article
- Rethinking intraoperative blood loss monitoring: a decision-oriented framework for clinically integrated assessment.International journal of burns and trauma · 2026Review
- Clinical Bedside Benchmarking Test for Measuring the Total Hemoglobin Concentration.Healthcare (Basel, Switzerland) · 2025Article
- Calculation methods for intraoperative blood loss: a literature review.BMC surgery · 2024Review
- Intraoperative Fluid Balance and Perioperative Complications in Ovarian Cancer Surgery.Annals of surgical oncology · 2024Article
- Estimating surgical blood loss: A review of current strategies in various clinical settings.SAGE open medicine · 2024Review
- Impact of Intraoperative Blood Transfusions on Survival Rates in Ovarian Cancer Patients.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBlood loss during major abdominal surgery is an essential parameter in the evaluation of strategies aimed at reducing perioperative bleeding. However, blood loss quantification remains unreliable and inaccurate. The aim of this study was to compare several methods of blood loss quantification-visual estimation by surgeon and anesthesiologist, the gravimetric method, the calculation method with spectrophotometric measurement. The spectrophotometric measurement is considered as the most accurate method.
methodsThe study was designed as a prospective observational cohort single-center study. We analyzed 61 patients who underwent elective liver or pancreatic resection. The anesthesiologists' and surgeons' estimate of blood loss was based on a visual assessment. The gravimetric method was based on weighing the suction canister and surgical drapes before and after use. The basis of calculation method was anthropometric and hematological parameters, we used López-Picado's formula. The spectrophotometric method was based on the spectrophotometric determination of hemoglobin mass in the lost blood. We compared the methods using paired t-test, non-parametric Wilcoxon test and Bland-Altman analysis.
resultsVisual estimation by surgeons and anesthesiologists, gravimetric measurement, and calculation method were significantly different from spectrophotometric measurement at the significance level α = 0.05. All methods overestimated blood loss which was measured by spectrophotometric method. The estimate by surgeons was the closest to the spectrophotometric measurement, difference 68.7 ml (95% confidence interval [CI]: -129.3--8.2).
conclusionsWe conclude that the estimate of blood loss by surgeons and anesthesiologists, as well as gravimetric method and calculation method are all significantly inaccurate in real surgical setting. We did not confirm the commonly accepted assumption that surgeons underestimate the blood loss.
trial registrationThe study was registered under the title " Blood Loss Quantification During Major Abdominal Surgery" at ClinicalTrials.gov with the registration number NCT05316649. Date of the first registration was 20/3/2022.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.