Evidence map›Paper›PMID 38166910›Full record

ArticleMalaria journal2024

Factors influencing patients' adherence to malaria artemisinin-based combination therapy in Kamuli District, Uganda.

Charles Bawate, Sylvia T Callender-Carter, Bernard Guyah, Collins Ouma

Open access · goldAbstract read
In one paragraph

Article in Malaria journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Charles BawateKamuli General Hospital-Kamuli District Local Government, Kamuli, Uganda. charlesbawate@yahoo.com.
Sylvia T Callender-CarterBugema University, Kampala, Uganda.
Bernard GuyahSchool of Public Health and Community Development, Maseno University, Maseno, Kenya.
Collins OumaSchool of Public Health and Community Development, Maseno University, Maseno, Kenya.
Maseno University · KEBugema University · UGKamuli General Hospital · UG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients' adherence to artemisinin-based combination therapy (ACT) is a malaria control strategy. Studies report varied experiences regarding patients' adherence to ACT. The study aimed at determining factors influencing patients' adherence to ACT for malaria in Kamuli, Uganda.

methodsIn a longitudinal study, 1266 participants at 8 public health facilities were enrolled. Equal numbers (422) were assigned to the three arms (no follow-up, day 2 and day 4). To establish the mean difference between groups, Student t-test was used and a chi-square test was used for proportionality. A multivariate logistic regression analysis was used to establish the influence of predictor variables on the dependent variable. Statistical significance was established at p < 0.05.

resultsA total of 844 patients were analysed. The median age was 20 years, majority (64.3%) were females. Overall patients' adherence was 588/844 (69.7%). At bivariate level, age (t-test = 2.258, p = 0.024), household head (χ

conclusionPatients' adherence to ACT is generally good in the studied population. However, patients' tendencies to save ACT for future use and sharing among family members is a threat, amidst the benefits associated with adherence. There is a need to educate all about adherence to medicines as prescribed, and tighten government medicine supply chain to avoid stock-outs.

Indexed as

AntimalarialsArtemisininsMalariaAdultDrug CombinationsDrug Therapy, CombinationFemaleHumansLongitudinal StudiesMaleUgandaYoung AdultAntimalarialsArtemisininsDrug CombinationsArtemisinin-based combination therapyPatients’ adherenceUganda

Identifiers

PMID38166910
PMCPMC10759708
OpenAlexW4390492928

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.