Evidence map›Paper›PMID 38166672›Full record

ArticleBMC gastroenterology2024

A retrospective cohort study on oesophageal food bolus obstruction in the North Denmark region in 2021-two thirds were never diagnosed with a cause.

Jacob Holmen Terkelsen, Martin Hollænder, Kasper Bredal, Sara Munk Nielsen, Kristoffer Vittrup Koed Thomsen, Amanda Baggerman, Emilia Ofverlind, Alptug Mertcan Koc, Hannah Pakes, Marco Bassam Mahdi and 6 more

Open access · goldAbstract read
In one paragraph

Article in BMC gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Wide discrepancy between best practice recommendations and real-life management of suspected eosinophilic esophagitis-associated food bolus impaction.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2025
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Jacob Holmen TerkelsenSchool of Medicine and Health, Aalborg University, Aalborg, Denmark.
Martin HollænderSchool of Medicine and Health, Aalborg University, Aalborg, Denmark.
Kasper BredalSchool of Medicine and Health, Aalborg University, Aalborg, Denmark.
Sara Munk NielsenSchool of Medicine and Health, Aalborg University, Aalborg, Denmark.
Kristoffer Vittrup Koed ThomsenDepartment of Emergency Medicine and Trauma Center, Aalborg University Hospital, Hobrovej 18-22, DK-9000, Aalborg, Denmark.
Amanda BaggermanDepartment of Emergency Medicine and Trauma Center, Aalborg University Hospital, Hobrovej 18-22, DK-9000, Aalborg, Denmark.
Emilia OfverlindSchool of Medicine and Health, Aalborg University, Aalborg, Denmark.
Alptug Mertcan KocDepartment of Emergency Medicine and Trauma Center, Aalborg University Hospital, Hobrovej 18-22, DK-9000, Aalborg, Denmark.
Hannah PakesDepartment of Emergency Medicine and Trauma Center, Aalborg University Hospital, Hobrovej 18-22, DK-9000, Aalborg, Denmark.
Marco Bassam MahdiDepartment of Emergency Medicine and Trauma Center, Aalborg University Hospital, Hobrovej 18-22, DK-9000, Aalborg, Denmark.
Sanne Ørnfeldt LarsenDepartment of Emergency Medicine and Trauma Center, Aalborg University Hospital, Hobrovej 18-22, DK-9000, Aalborg, Denmark.
Vanessa Parra GonzalezDepartment of Emergency Medicine and Trauma Center, Aalborg University Hospital, Hobrovej 18-22, DK-9000, Aalborg, Denmark.
Johannes RiisDepartment of Emergency Medicine and Trauma Center, Aalborg University Hospital, Hobrovej 18-22, DK-9000, Aalborg, Denmark.
Line Tegtmeier FrandsenDepartment of Emergency Medicine and Trauma Center, Aalborg University Hospital, Hobrovej 18-22, DK-9000, Aalborg, Denmark.
Dorte MelgaardDepartment of Gastroenterology and Hepatology, Aalborg University Hospital, Aalborg, Denmark.
Anne Lund KrarupDepartment of Emergency Medicine and Trauma Center, Aalborg University Hospital, Hobrovej 18-22, DK-9000, Aalborg, Denmark. apslk@rn.dk.
Aalborg University · DKAalborg University Hospital · DKNorth Denmark Region · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFood bolus obstruction (FBO) leading to hospital treatment is often associated with eosinophilic oesophagitis (EoE), stenosis, or oesophageal cancer (1). Danish national guidelines recommend that patients with FBO undergo a diagnostic upper endoscopy within two weeks of presentation to exclude possible malignancy, and histological evaluation of eight biopsies (2, 3).

aimsThe aims of this study were to (1) report the incidence and describe the causes and treatment of FBO in the North Denmark Region (NDR), (2) determine the proportion of patients who underwent upper endoscopy and biopsy according to regional and national guidelines, and (3) identify International Classification of Diseases 10th Revision (ICD-10) diagnosis and procedure codes applied to the hospital visits due to FBO in the NDR.

methodsAmong all acute hospital visits in the NDR in 2021, all visits with ICD-10 codes possibly reflecting FBO, as well as a random sample of 14,400 visits with unspecific ICD-10 codes (R and Z codes), were screened manually for possible FBO. Diagnosis, follow-up, and treatment of all patients with FBO were recorded.

resultsThe median patient age was 66.0 (Q1-Q3: 49.8-81.0) years, and half of the patients had experienced FBO before. Two thirds of patients (66.0%) were never diagnosed with a cause of FBO, followed by 17.3% with EoE. 30% of patients did not undergo upper endoscopy within two weeks of the hospital visit, and 50.7% were never biopsied in the oesophagus. Of 1886 hospital visits with registry ICD-10 codes that possibly reflected FBO, 8.4% were due to FBO, while FBO was present in 0.028% of the random sample of unspecific ICD-10 codes.

conclusionsMost hospitalized FBO patients in the NDR in 2021 were never diagnosed with a cause. In these patients there is a high risk of overlooked EoE or upper gastrointestinal cancers. The area needs immediate focus and changed routines to improve treatment and prevent new FBO.

Indexed as

Eosinophilic EsophagitisEsophageal StenosisAgedAged, 80 and overDenmarkEnteritisEosinophiliaGastritisHumansMiddle AgedRetrospective StudiesEosinophilic oesophagitisFood Bolus ImpactionFood Bolus obstructionOesophageal cancerOesophagusUpper Endoscopy

Identifiers

PMID38166672
PMCPMC10759704
OpenAlexW4390501729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.