Evidence map›Paper›PMID 38166530›Full record

ReviewBMC bioinformatics2024

Graph embedding on mass spectrometry- and sequencing-based biomedical data.

Edwin Alvarez-Mamani, Reinhard Dechant, César A Beltran-Castañón, Alfredo J Ibáñez

Abstract readReview
In one paragraph

Review in BMC bioinformatics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Edwin Alvarez-MamaniEngineering Department, Pontificia Universidad Católica del Perú, San Miguel, Lima, Peru.
Reinhard DechantInstitute for Omics Sciences and Applied Biotechnology (ICOBA PUCP), Pontificia Universidad Católica del Perú, San Miguel, Lima, Peru.
César A Beltran-CastañónEngineering Department, Pontificia Universidad Católica del Perú, San Miguel, Lima, Peru.
Alfredo J IbáñezInstitute for Omics Sciences and Applied Biotechnology (ICOBA PUCP), Pontificia Universidad Católica del Perú, San Miguel, Lima, Peru. aibanez@pucp.edu.pe.

Funding

Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica (CONCYTEC) 174-2020-FONDECYTMax-Planck-Gesellschaft "The Max Planck Partner Group" (Between the Max Planck Institute for Chemical Ecology-Jena and the Pontificia Universidad Católica del Perú)
6 · The paper itself

Abstract

Graph embedding techniques are using deep learning algorithms in data analysis to solve problems of such as node classification, link prediction, community detection, and visualization. Although typically used in the context of guessing friendships in social media, several applications for graph embedding techniques in biomedical data analysis have emerged. While these approaches remain computationally demanding, several developments over the last years facilitate their application to study biomedical data and thus may help advance biological discoveries. Therefore, in this review, we discuss the principles of graph embedding techniques and explore the usefulness for understanding biological network data derived from mass spectrometry and sequencing experiments, the current workhorses of systems biology studies. In particular, we focus on recent examples for characterizing protein-protein interaction networks and predicting novel drug functions.

Indexed as

AlgorithmsSocial MediaData AnalysisHumansMass SpectrometryProtein Interaction MapsBiological networkBiomedical dataGraph embedding

Identifiers

PMID38166530
PMCPMC10763173

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.