ReviewRadiology. Cardiothoracic imaging2023
Mitral Annular Disjunction: Review of an Increasingly Recognized Mitral Valve Entity.
Review in Radiology. Cardiothoracic imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 21 citations in OpenAlex.
- Mitral annular disjunction and mitral valve prolapse: echocardiographic-MRI insights into cardiac function.The international journal of cardiovascular imaging · 2026Article
- Malignant Mitral Valve Prolapse With Life-Threatening Ventricular Arrhythmias: A Multidisciplinary Team-Guided Stepwise Management.JACC. Case reports · 2026Article
- Association between Mitral Valve Pathology and Ventricular Ectopy in the Pediatric Marfan Population.Pediatric cardiology · 2026Article
- Minimally invasive cardiac surgery - coronary artery bypass grafting in patients with low left ventricular ejection fraction.BMC cardiovascular disorders · 2026Article
- Near-Fatal Arrhythmia From Severe Mitral Annular Disjunction.Case reports in cardiology · 2026Article
- Mitral Valve Surgery with and Without Mitral Annular Disjunction: A Meta-Analysis.Journal of cardiovascular development and disease · 2025Review
- Late gadolinium enhancement imaging and sudden cardiac death.European heart journal · 2025Review
- Mitral annular disjunction and mitral valve prolapse: long-term risk of ventricular arrhythmias after surgery.European heart journal · 2025Article
- Sudden cardiac death unveiling a mitral annular disjunction in a young man: The role of multimodal cardiac imaging for diagnosis.Journal of cardiology cases · 2025Article
- Review
- The Prevalence, Pathophysiological Role and Determinants of Mitral Annular Disjunction Among Patients with Mitral Valve Prolapse: A Systematic Review.Journal of clinical medicine · 2025Review
- Mitral Annular Disjunction: Case Report and Literature Review.US cardiology · 2025Review
- Prevalence of Mitral Annular Disjunction at Cardiac MRI: Results from a Multicenter Registry.Radiology. Cardiothoracic imaging · 2024Observational
- Mitral annular disjunction in Marfan syndrome: a multicenter cardiovascular magnetic resonance study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic ResonanceArticle
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mitral annular disjunction (MAD) refers to atrial displacement of the hinge point of the mitral valve annulus from the ventricular myocardium. MAD leads to paradoxical expansion of the annulus in systole and may often be associated with mitral valve prolapse (MVP), leaflet degeneration, myocardial and papillary muscle fibrosis, and, potentially, malignant cardiac arrhythmias. Patients with MAD and MVP may present similarly, and MAD is potentially the missing link in explaining why some patients with MVP experience adverse outcomes. Patients with a 5 mm or longer MAD distance have an elevated risk of malignant cardiac arrhythmia compared with those with a shorter MAD distance. Evaluation for MAD is an important component of cardiac imaging, especially in patients with MVP and unexplained cardiac arrhythmias. Cardiac MRI is an important diagnostic tool that aids in recognizing and quantifying MAD, MVP, and fibrosis in the papillary muscle and myocardium, which may predict and help improve outcomes following electrophysiology procedures and mitral valve surgery. This article reviews the history, pathophysiology, controversy, prevalence, clinical implications, and imaging considerations of MAD, focusing on cardiac MRI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.