Evidence map›Paper›PMID 38166089›Full record

ArticlePloS one2024

HIV prevalence and awareness among adults presenting for enrolment into a study of people at risk for HIV in Kisumu County, Western Kenya.

Valentine Sing'oei, Chiaka Nwoga, Adam Yates, John Owuoth, June Otieno, Erica Broach, Qun Li, Zebiba Hassen, Michelle Imbach, Mark Milazzo and 6 more

Abstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  4. Loss to Follow-Up and Visit Nonadherence in an HIV Incidence Cohort in Kisumu, Kenya.Journal of acquired immune deficiency syndromes (1999) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Valentine Sing'oeiHJF Medical Research International, Kisumu, Kenya.
Chiaka NwogaU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, United States of America.ORCID https://orcid.org/0000-0002-4514-330X
Adam YatesU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, United States of America.
John OwuothHJF Medical Research International, Kisumu, Kenya.
June OtienoUnited States Army Medical Research Directorate-Africa, Nairobi, Kenya.
Erica BroachU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, United States of America.
Qun LiU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, United States of America.
Zebiba HassenU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, United States of America.
Michelle ImbachU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, United States of America.
Mark MilazzoU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, United States of America.
Tsedal MebrahtuU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, United States of America.
Merlin L RobbHenry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, United States of America.ORCID https://orcid.org/0000-0003-3949-9649
Julie A AkeU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, United States of America.
Christina S PolyakU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, United States of America.
Trevor A CrowellU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, United States of America.ORCID https://orcid.org/0000-0001-5947-265X
RV393 Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDespite declines in new HIV diagnoses both globally and in Kenya, parts of Western Kenya still report high HIV prevalence and incidence. We evaluated HIV prevalence to inform the development of policies for strategic and targeted HIV prevention interventions.

methodsAdult participants aged 18-35 years were recruited in Kisumu County and screened for HIV for a prospective HIV incidence cohort. Questionnaires assessed HIV-associated risk behaviors. Participants who tested positive for HIV were disaggregated into groups based on prior knowledge of their HIV status: previously-diagnosed and newly-diagnosed. In separate analyses by prior knowledge, robust Poisson regression was used to estimate prevalence ratios (PRs) and 95% confidence intervals (CIs) for factors potentially associated with a positive HIV test in each group, as compared to participants without HIV.

resultsOf 1059 participants tested for HIV, 196 (18.5%) had a positive HIV test. Among PLWH, 78 (39.8%) were newly diagnosed with HIV at screening. After adjusting for other variables, previously-diagnosed HIV was more common among females than males (PR 2.70, 95%CI 1.69-4.28), but there was no observed sex difference in newly-diagnosed HIV prevalence (PR 1.05, 95%CI 0.65-1.69). Previously-diagnosed HIV was also more common among people reporting consistent use of condoms with primary sexual partners as compared to inconsistent condom use (PR 3.19, 95%CI 2.09-4.86), but newly-diagnosed HIV was not associated with such a difference between consistent and inconsistent condom use (PR 0.73, 95%CI 0.25-2.10).

conclusionPrevalence of newly-diagnosed HIV was high, at approximately 8% of participants, and not statistically different between genders, highlighting the need for improved HIV case finding regardless of sex. The higher prevalence of previously-diagnosed HIV in female participants may reflect higher rates of HIV testing through more encounters with the healthcare system. Higher prevalence of consistent condom use amongst those previously-diagnosed suggests behavioral change to reduce HIV transmission, a potential benefit of policies to facilitate earlier HIV diagnosis.

Indexed as

HIV InfectionsAdultCondomsFemaleHumansKenyaMalePrevalenceProspective StudiesSafe SexSexual Partners

Identifiers

PMID38166089
PMCPMC10760834

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.