Evidence map›Paper›PMID 38165558›Full record

ArticleGeneral thoracic and cardiovascular surgery2024

Short-term effects of preoperative nutritional intervention in lung surgery for malignant tumors: a single-center prospective study.

Mamoru Takahashi, Harutaro Okada, Mako Kogaki, Rio Shirokihara, Yuka Kawate, Hironobu Tokumasu, Akihiro Aoyama

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Article in General thoracic and cardiovascular surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 0 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mamoru TakahashiDepartment of Thoracic Surgery, Kyoto Katsura Hospital, 17 Yamada Hirao, Nishikyo, Kyoto, 615-8256, Japan. mt10947@kuhp.kyoto-u.ac.jp.ORCID http://orcid.org/0000-0001-6141-0554
Harutaro OkadaDepartment of Thoracic Surgery, Kyoto Katsura Hospital, 17 Yamada Hirao, Nishikyo, Kyoto, 615-8256, Japan.
Mako KogakiDepartment of Nutrition, Kyoto Katsura Hospital, Kyoto, Japan.
Rio ShirokiharaDepartment of Nutrition, Kyoto Katsura Hospital, Kyoto, Japan.
Yuka KawateDepartment of Nutrition, Kyoto Katsura Hospital, Kyoto, Japan.
Hironobu TokumasuDepartment of Clinical Research, Kurashiki Central Hospital, Okayama, Japan.
Akihiro AoyamaDepartment of Thoracic Surgery, Kyoto Katsura Hospital, 17 Yamada Hirao, Nishikyo, Kyoto, 615-8256, Japan.
Kyoto Katsura Hospital · JPKurashiki Central Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPreoperative malnutrition is a risk factor for postoperative morbidity and mortality in patients with lung cancer. Assessing the preoperative nutritional status should be considered essential for patients scheduled to undergo lung surgery. This prospective study aimed to investigate whether preoperative nutritional intervention improves the nutritional conditions and short-term postoperative outcomes.

methodsThe primary endpoints included safety, feasibility and short-term therapeutic efficacy of preoperative nutritional intervention. Patients with clinical stage I-III non-small cell lung cancer (histologically proven or suspected) were screened. Patient enrollment was conducted between January 2021 and December 2022. A total of 15 patients were included in the analysis. Patients with a preoperative prognostic nutritional index of < 45 were considered eligible. All participants received preoperative nutritional intervention. The trajectories of prognostic nutritional index and the incidence of postoperative complication rates in the intervention group were investigated.

resultsNo adverse events were observed during the nutritional intervention. The pre-intervention and post-intervention prognostic nutritional indices were 42.2 (39.8-44.5), and 43.1 (41.4-45.9), respectively (p = 0.04). The postoperative complication rate was 26.7% (n = 15).

conclusionsThis is the first prospective study to report the preoperative trajectories of prognostic nutritional index in patients undergoing lung cancer surgery. Our results suggest the safety and feasibility of preoperative nutritional intervention. Further research, such as randomized clinical trials, is warranted to investigate clinical efficacy and optimal nutritional interventions for lung surgery for malignant tumors.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsMalnutritionNutritional StatusPostoperative ComplicationsAgedFeasibility StudiesFemaleHumansMaleMiddle AgedNutrition AssessmentPneumonectomyPreoperative CareProspective StudiesRisk FactorsNon-small cell lung cancerPreoperative nutritional interventionPrognostic nutritional indexProspective study

Identifiers

PMID38165558
OpenAlexW4390496878

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.