ArticleJAMA2024
Partial Heart Transplant in a Neonate With Irreparable Truncal Valve Dysfunction.
Article in JAMA, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 71 citations in OpenAlex.
- Mitral Valve Repair vs. Replacement: Hemodynamics in Valve Surgery.Reviews in cardiovascular medicine · 2026Review
- Global, regional, and national burden and trends of congenital birth defects from 1990 to 2021: epidemiological trends, health inequalities, and COVID-19 impact.Translational pediatrics · 2026Article
- Article
- Semilunar Valves in Pediatric Orthotopic Heart Transplants Grow at a Slower Rate than Controls.Pediatric cardiology · 2026Article
- Valve function during graft rejection and before graft failure in pediatric heart transplant recipients.JTCVS open · 2026Article
- A custom preservation solution extends the ex vivo availability of living heart valves for transplantation.JTCVS open · 2025Article
- A structured institutional framework for establishing a living allogenic valve transplant program.JHLT open · 2025Article
- Indications and Practical Considerations for Partial Heart Transplantation.The Annals of thoracic surgery · 2025Review
- Intramuscular Tacrolimus Pharmacokinetics in a Pediatric Porcine Model for Partial Heart Transplantation.Transplantation proceedings · 2025Article
- Expanding the use of 3D printing in congenital heart surgery.Translational pediatrics · 2025Review
- Article
- Innovative strategies to increase cardiac donor availability.World journal of transplantation · 2025Review
- Semilunar Valve Function After Rejection in Heart Transplant Recipients: Implications for Partial Heart Transplantation.Pediatric transplantation · 2025Article
- Primary repair of common arterial trunk: A systematic meta-analysis of short- and long-term outcomes.JTCVS open · 2025Article
- Pediatric partial heart xenotransplantation as an early use case of xenograft tissue.Future cardiology · 2025Review
- Partial Heart Transplants Require Immunosuppression in Growing Piglets.Transplantation · 2025Article
- Baseline Characterization of Swine Leukocyte Antigen Diversity in GFP-Expressing Domestic Swine.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Article
- Viability of Partial Heart Transplant Grafts During Prolonged Cold Preservation Suggests That Longer Donor Cold Chain Logistics May Be Feasible.Pediatric transplantation · 2025Article
- Partial Heart Transplantation Promotes Organ Stewardship: Domino Hearts and Split Roots.Annals of thoracic surgery short reports · 2025Article
- Suitability of Infant Heart Transplant Recipients to Serve as Domino Partial Heart Transplant Donors.Pediatric transplantation · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Importance: The treatment of neonates with irreparable heart valve dysfunction remains an unsolved problem because there are no heart valve implants that grow. Therefore, neonates with heart valve implants are committed to recurrent implant exchanges until an adult-sized valve can fit. Objective: To deliver the first heart valve implant that grows. Design, Setting, and Participants: Case report from a pediatric referral center, with follow-up for more than 1 year. Participants were a recipient neonate with persistent truncus arteriosus and irreparable truncal valve dysfunction and a donor neonate with hypoxic-ischemic brain injury. Intervention: First-in-human transplant of the part of the heart containing the aortic and pulmonary valves. Main Outcomes and Measures: Transplanted valve growth and hemodynamic function. Results: Echocardiography demonstrated adaptive growth and excellent hemodynamic function of the partial heart transplant valves. Conclusions and Relevance: In this child, partial heart transplant delivered growing heart valve implants with a good outcome at age 1 year. Partial heart transplants may improve the treatment of neonates with irreparable heart valve dysfunction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.