Evidence map›Paper›PMID 38165368›Full record

Observational studyNeurology2024

Association of Neighborhood-Level Socioeconomic Factors With Delay to Hospital Arrival in Patients With Acute Stroke.

Rachel Forman, Rita Okumu, Razaz Mageid, Anna Baker, Dalton Neu, Ranisha Parker, Reza Peyravi, Joseph L Schindler, Lauren H Sansing, Kevin N Sheth and 6 more

Erratum issuedAbstract readObservational Study
In one paragraph

Observational study in Neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Hospital Socioeconomic Status and Acute Stroke Treatment in the United States.Cerebrovascular diseases (Basel, Switzerland) · 2026
    Article
  2. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Rachel FormanFrom the Departments of Neurology (R.F., R.O., R.M., A.B., D.N., R. Parker, R. Peyravi, J.L.S., L.H.S., K.N.S., A.H., A.J., R.N., R.S.) and Emergency Medicine (C.W.), Yale School of Medicine, New Haven, CT; and Department of Biostatistics (J.W.), Yale School of Public Health, New Haven, CT.
Rita OkumuFrom the Departments of Neurology (R.F., R.O., R.M., A.B., D.N., R. Parker, R. Peyravi, J.L.S., L.H.S., K.N.S., A.H., A.J., R.N., R.S.) and Emergency Medicine (C.W.), Yale School of Medicine, New Haven, CT; and Department of Biostatistics (J.W.), Yale School of Public Health, New Haven, CT.
Razaz MageidFrom the Departments of Neurology (R.F., R.O., R.M., A.B., D.N., R. Parker, R. Peyravi, J.L.S., L.H.S., K.N.S., A.H., A.J., R.N., R.S.) and Emergency Medicine (C.W.), Yale School of Medicine, New Haven, CT; and Department of Biostatistics (J.W.), Yale School of Public Health, New Haven, CT.
Anna BakerFrom the Departments of Neurology (R.F., R.O., R.M., A.B., D.N., R. Parker, R. Peyravi, J.L.S., L.H.S., K.N.S., A.H., A.J., R.N., R.S.) and Emergency Medicine (C.W.), Yale School of Medicine, New Haven, CT; and Department of Biostatistics (J.W.), Yale School of Public Health, New Haven, CT.
Dalton NeuFrom the Departments of Neurology (R.F., R.O., R.M., A.B., D.N., R. Parker, R. Peyravi, J.L.S., L.H.S., K.N.S., A.H., A.J., R.N., R.S.) and Emergency Medicine (C.W.), Yale School of Medicine, New Haven, CT; and Department of Biostatistics (J.W.), Yale School of Public Health, New Haven, CT.
Ranisha ParkerFrom the Departments of Neurology (R.F., R.O., R.M., A.B., D.N., R. Parker, R. Peyravi, J.L.S., L.H.S., K.N.S., A.H., A.J., R.N., R.S.) and Emergency Medicine (C.W.), Yale School of Medicine, New Haven, CT; and Department of Biostatistics (J.W.), Yale School of Public Health, New Haven, CT.
Reza PeyraviFrom the Departments of Neurology (R.F., R.O., R.M., A.B., D.N., R. Parker, R. Peyravi, J.L.S., L.H.S., K.N.S., A.H., A.J., R.N., R.S.) and Emergency Medicine (C.W.), Yale School of Medicine, New Haven, CT; and Department of Biostatistics (J.W.), Yale School of Public Health, New Haven, CT.ORCID 0009-0007-0854-6568
Joseph L SchindlerFrom the Departments of Neurology (R.F., R.O., R.M., A.B., D.N., R. Parker, R. Peyravi, J.L.S., L.H.S., K.N.S., A.H., A.J., R.N., R.S.) and Emergency Medicine (C.W.), Yale School of Medicine, New Haven, CT; and Department of Biostatistics (J.W.), Yale School of Public Health, New Haven, CT.
Lauren H SansingFrom the Departments of Neurology (R.F., R.O., R.M., A.B., D.N., R. Parker, R. Peyravi, J.L.S., L.H.S., K.N.S., A.H., A.J., R.N., R.S.) and Emergency Medicine (C.W.), Yale School of Medicine, New Haven, CT; and Department of Biostatistics (J.W.), Yale School of Public Health, New Haven, CT.
Kevin N ShethFrom the Departments of Neurology (R.F., R.O., R.M., A.B., D.N., R. Parker, R. Peyravi, J.L.S., L.H.S., K.N.S., A.H., A.J., R.N., R.S.) and Emergency Medicine (C.W.), Yale School of Medicine, New Haven, CT; and Department of Biostatistics (J.W.), Yale School of Public Health, New Haven, CT.ORCID 0000-0003-2003-5473
Adam de HavenonFrom the Departments of Neurology (R.F., R.O., R.M., A.B., D.N., R. Parker, R. Peyravi, J.L.S., L.H.S., K.N.S., A.H., A.J., R.N., R.S.) and Emergency Medicine (C.W.), Yale School of Medicine, New Haven, CT; and Department of Biostatistics (J.W.), Yale School of Public Health, New Haven, CT.ORCID 0000-0001-8178-8597
Adam JasneFrom the Departments of Neurology (R.F., R.O., R.M., A.B., D.N., R. Parker, R. Peyravi, J.L.S., L.H.S., K.N.S., A.H., A.J., R.N., R.S.) and Emergency Medicine (C.W.), Yale School of Medicine, New Haven, CT; and Department of Biostatistics (J.W.), Yale School of Public Health, New Haven, CT.ORCID 0000-0001-9092-3607
Reshma NarulaFrom the Departments of Neurology (R.F., R.O., R.M., A.B., D.N., R. Parker, R. Peyravi, J.L.S., L.H.S., K.N.S., A.H., A.J., R.N., R.S.) and Emergency Medicine (C.W.), Yale School of Medicine, New Haven, CT; and Department of Biostatistics (J.W.), Yale School of Public Health, New Haven, CT.
Charles WiraFrom the Departments of Neurology (R.F., R.O., R.M., A.B., D.N., R. Parker, R. Peyravi, J.L.S., L.H.S., K.N.S., A.H., A.J., R.N., R.S.) and Emergency Medicine (C.W.), Yale School of Medicine, New Haven, CT; and Department of Biostatistics (J.W.), Yale School of Public Health, New Haven, CT.
Joshua WarrenFrom the Departments of Neurology (R.F., R.O., R.M., A.B., D.N., R. Parker, R. Peyravi, J.L.S., L.H.S., K.N.S., A.H., A.J., R.N., R.S.) and Emergency Medicine (C.W.), Yale School of Medicine, New Haven, CT; and Department of Biostatistics (J.W.), Yale School of Public Health, New Haven, CT.
Richa SharmaFrom the Departments of Neurology (R.F., R.O., R.M., A.B., D.N., R. Parker, R. Peyravi, J.L.S., L.H.S., K.N.S., A.H., A.J., R.N., R.S.) and Emergency Medicine (C.W.), Yale School of Medicine, New Haven, CT; and Department of Biostatistics (J.W.), Yale School of Public Health, New Haven, CT.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

BACKGROUND AND

objectivesDelivery of acute ischemic stroke (AIS) therapies is contingent on the duration from last known well (LKW) to emergency department arrival time (EDAT). One reason for treatment ineligibility is delay in presentation to the hospital. We evaluate patient and neighborhood characteristics associated with time from LKW to EDAT.

methodsThis was a retrospective observational study of patients presenting to the Yale New Haven Hospital in the AIS code pathway from 2010 to 2020. Patients presenting within 4.5 hours from LKW who were recorded in the institutional Get With the Guidelines Stroke registry were classified as early while those presenting beyond 4.5 hours were designated as late. Temporal trends in late presentation were explored by univariate logistic regression. Using variables significant in univariate analysis at

resultsA total of 2,643 patients with AIS from 2010 to 2020 were included (63.4% presented late and 36.6% presented early). The frequency of late presentation increased significantly from 68% in 2010 to 71% in 2020 ( DISCUSSION: In addition to patient-level factors, socioeconomic deprivation of neighborhood of residence contributes to delays in hospital presentation for AIS. These findings may provide opportunities for targeted interventions to improve presentation times in at-risk communities.

Indexed as

Emergency Medical ServicesIschemic StrokeStrokeHospitalsHumansSocioeconomic FactorsUnited States

Identifiers

PMID38165368
PMCPMC10834135

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.