Evidence map›Paper›PMID 38165334›Full record

ArticleNeurology2024

Association Between Body Mass Index and Functional Outcomes in Patients With Intracerebral Hemorrhage.

Andrea Becerril-Gaitan, Dale Ding, Natasha Ironside, Andrew M Southerland, Bradford B Worrall, Fernando D Testai, Matthew L Flaherty, Mitchell S Elkind, Sebastian Koch, Gene Sung and 14 more

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In one paragraph

Article in Neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 1 institution in 1 country.

Andrea Becerril-GaitanFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0000-0003-4606-5646
Dale DingFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0000-0002-2627-446X
Natasha IronsideFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0000-0002-9390-1574
Andrew M SoutherlandFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0000-0002-3646-358X
Bradford B WorrallFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0000-0001-9386-4091
Fernando D TestaiFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0000-0002-7355-4915
Matthew L FlahertyFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0000-0002-6247-010X
Mitchell S ElkindFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0000-0003-2562-1156
Sebastian KochFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.
Gene SungFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.
Steven J KittnerFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0000-0002-8457-8744
Douglas J MaysonFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0009-0007-4312-7174
Nicole GonzalesFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0000-0002-0419-0740
Jacob L McCauleyFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0000-0002-1805-1733
Marc MalkoffFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0000-0002-6665-3114
Christiana E HallFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.
Michael R FrankelFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0000-0002-4424-7297
Michael L JamesFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0000-0002-8715-5210
Christopher D AndersonFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0000-0002-0053-2002
Jaroslaw AronowskiFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0000-0002-9256-7973
Sean I SavitzFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0000-0003-4637-1790
Daniel WooFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0000-0002-2466-7155
Ching-Jen ChenFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.ORCID 0000-0002-7830-9273
ERICH investigatorsFrom the Departments of Neurosurgery (A.B.-G., C.-J.C.) and Neurology (J.A., S.I.S.), The University of Texas Health Science Center at Houston; Department of Neurosurgery (D.D.), University of Louisville, KY; Department of Neurosurgery (N.I.); Departments of Neurology and Public Health Sciences (A.M.S., B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; Department of Neurology (M.L.F., D.W.), University of Cincinnati, OH; Department of Neurology (M.S.E.), Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York; Department of Neurology (S.K.) and John P. Hussman Institute for Human Genomics (J.L.M.), University of Miami Miller School of Medicine, FL; Department of Neurology and Neurocritical Care and Stroke (G.S.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology (D.J.M.), MedStar Georgetown University Hospital, Washington, DC; Department of Neurology (N.G.), University of Colorado School of Medicine, Aurora; Departments of Neurology and Neurosurgery (M.M.), University of Tennessee Health Sciences, Memphis; Department of Neurology (C.E.H.), University of Texas Southwestern, Dallas; Department of Neurology (M.R.F.), Emory University, Grady Memorial Hospital, Atlanta, GA; Departments of Anesthesiology and Neurology (M.L.J.), Duke Clinical Research Institute, Duke University, Durham, NC; and Henry and Allison McCane Center for Brain Health and Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Massachusetts, Boston.
University of Illinois Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesEvidence of the so-called "obesity paradox," which refers to the protective effect and survival benefit of obesity in patients with spontaneous intracerebral hemorrhage (ICH), remains controversial. This study aims to determine the association between body mass index (BMI) and functional outcomes in patients with ICH and whether it is modified by race/ethnicity.

methodsIncluded individuals were derived from the Ethnic/Racial Variations of Intracerebral Hemorrhage study, which prospectively recruited 1,000 non-Hispanic White, 1,000 non-Hispanic Black, and 1,000 Hispanic patients with spontaneous ICH. Only patients with available BMI were included. The primary outcome was 90-day mortality. Secondary outcomes were mortality at discharge, modified Rankin Scale (mRS), Barthel Index, and self-reported health status measures at 90 days. Associations between BMI and ICH outcomes were assessed using univariable and multivariable logistic, ordinal, and linear regression models, as appropriate. Sensitivity analyses after excluding frail patients and by patient race/ethnicity were performed.

resultsA total of 2,841 patients with ICH were included. The median age was 60 years (interquartile range 51-73). Most patients were overweight (n = 943; 33.2%) or obese (n = 1,032; 36.3%). After adjusting for covariates, 90-day mortality was significantly lower among overweight and obese patients than their normal weight counterparts (adjusted odds ratio [aOR] = 0.71 [0.52-0.98] and aOR = 0.70 [0.50-0.97], respectively). Compared with patients with BMI <25 kg/m

conclusionWe demonstrated that a higher BMI is associated with decreased mortality, improved functional outcomes, and better self-reported health status at 90 days, thus supporting the paradoxical role of obesity in patients with ICH. The beneficial effect of high BMI does not seem to be modified by race/ethnicity or sex, whereas age may play a significant role in patient functional outcomes.

Indexed as

EthnicityOverweightBody Mass IndexCerebral HemorrhageHumansMiddle AgedObesity

Identifiers

PMID38165334
PMCPMC10870743
OpenAlexW4390043687

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