Evidence map›Paper›PMID 38165204›Full record

ArticleActa otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale2024

Type IV optic nerve and Onodi cell: is there a risk of injury during sphenoid sinus surgery?

Gian Luca Fadda, Anastasia Urbanelli, Alessio Petrelli, Marta Trossarello, Letizia Nitro, Alberto Maria Saibene, Eugenio De Corso, Dario Gned, Marco Panfili, Giovanni Cavallo

Open access · goldAbstract read
In one paragraph

Article in Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Determinants of sphenoid sinus ostium localization: implications for safer endoscopic sinus surgery.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Temporal trends of blood eosinophilia in severe uncontrolled CRSwNP treated with dupilumab: a real-life study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Gian Luca FaddaDepartment of Otorhinolaryngology, University of Turin, "San Luigi Gonzaga" Hospital, Orbassano (TO), Italy.
Anastasia UrbanelliDepartment of Otorhinolaryngology, University of Turin, "San Luigi Gonzaga" Hospital, Orbassano (TO), Italy.
Alessio PetrelliNational Institute for Health, Migration and Poverty (INMP), Rome, Italy.
Marta TrossarelloDepartment of Otorhinolaryngology, University of Turin, "San Luigi Gonzaga" Hospital, Orbassano (TO), Italy.
Letizia NitroOtolaryngology Unit, "Santi Paolo e Carlo" Hospital, Department of Health Sciences, University of Milan, Milan, Italy.
Alberto Maria SaibeneOtolaryngology Unit, "Santi Paolo e Carlo" Hospital, Department of Health Sciences, University of Milan, Milan, Italy.
Eugenio De CorsoOtorhinolaryngology, "A. Gemelli" Unversitary Hospital IRCCS, Rome, Italy.
Dario GnedDepartment of Diagnostic Imaging, University of Turin, "San Luigi Gonzaga" Hospital, Orbassano (TO), Italy.
Marco PanfiliUnit of Radiology, "A. Gemelli" University Hospital Foundation IRCCS, Rome, Italy.
Giovanni CavalloDepartment of Otorhinolaryngology, University of Turin, "San Luigi Gonzaga" Hospital, Orbassano (TO), Italy.
Ospedale San Luigi Gonzaga · ITAgostino Gemelli University Polyclinic · ITAOL (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to determine the prevalence and types of Onodi cells through computed tomography and investigate the relationship between Onodi cell and the surrounding structures, paying particular attention to the risky proximity to the optic nerve canal. Methods: In this study, 430 computed tomography scans of paranasal sinuses were analysed to establish the prevalence and different types of Onodi cells. Furthermore, the relationship between Onodi cell and different patterns of sphenoid sinus pneumatisation and surrounding structures were investigated. Special attention was paid to the relationship between Onodi cell and the optic nerve canal, particularly in cases when the optic nerve canal was bulging by more than 50% into the Onodi cell (Type IV). Results: The Onodi cell was detected in 21.6% of cases, with the most common being Type I (48.5% right, 54.3% left). Type IV bulging of the optic nerve canal into the Onodi cell was observed in 47.1% of cases on the right side, 41.2% on the left side and bilateral in 11.7% of cases. Conclusions: In our series, we observed a high prevalence of Type IV optic nerve bulging into the Onodi cell. For this reason, we suggest that clinicians should always try to identify it in a pre-operative setting with computed tomography to avoid catastrophic consequences during endoscopic sinus surgery approaching the sphenoid area.

Indexed as

Paranasal SinusesSphenoid SinusHumansOptic NerveSphenoid BoneTomography, X-Ray Computedcomputed tomographyendoscopic sinus surgeryOnodi celloptic nervesphenoid sinus

Identifiers

PMID38165204
PMCPMC10914358
OpenAlexW4390507711

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.