Evidence map›Paper›PMID 38164967›Full record

ArticleThe Journal of infectious diseases2024

Clinical Manifestations of an Outbreak of Monkeypox Virus in Captive Chimpanzees in Cameroon, 2016.

Stephanie C Brien, Matthew LeBreton, Jeffrey B Doty, Matthew R Mauldin, Clint N Morgan, Emily G Pieracci, Jana M Ritter, Audrey Matheny, Bibila G Tafon, Ubald Tamoufe and 9 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 4 countries.

Stephanie C BrienRoyal (Dick) School of Veterinary Studies and the Roslin Institute, Easter Bush Campus, The University of Edinburgh, Roslin, United Kingdom.ORCID 0000-0002-0311-2898
Matthew LeBretonMosaic, Yaoundé, Cameroon.
Jeffrey B DotyDivision of High Consequence Pathogens and Pathology, US Centers for Disease Control and Prevention, Atlanta, GA, USA.
Matthew R MauldinDivision of High Consequence Pathogens and Pathology, US Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0002-3807-2339
Clint N MorganDivision of High Consequence Pathogens and Pathology, US Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0001-8646-8920
Emily G PieracciDivision of High Consequence Pathogens and Pathology, US Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0002-7735-6051
Jana M RitterDivision of High Consequence Pathogens and Pathology, US Centers for Disease Control and Prevention, Atlanta, GA, USA.
Audrey MathenyDivision of High Consequence Pathogens and Pathology, US Centers for Disease Control and Prevention, Atlanta, GA, USA.
Bibila G TafonApe Action Africa, Mefou Park, Cameroon.
Ubald TamoufeMetabiota, Yaoundé, Cameroon.
Alain D MissoupZoology Unit, Laboratory of Biology and Physiology of Animal Organisms, Faculty of Science, University of Douala, Cameroon.
Julius NwobegahayCentre for Army Health Research, Yaoundé, Cameroon.
Jean Michel TakuoMetabiota, Yaoundé, Cameroon.
Felix NkomMetabiota, Yaoundé, Cameroon.
Moctar M M MouicheMosaic, Yaoundé, Cameroon.
Jean Marc K FeussomCameroon Epidemiological Network for Animal Diseases, Directorate of Veterinary Services, Ministry of Livestock, Fisheries and Animal Industries, Yaoundé, Cameroon.
Kimberly WilkinsDivision of High Consequence Pathogens and Pathology, US Centers for Disease Control and Prevention, Atlanta, GA, USA.
Abel WadeNational Veterinary Laboratory, Garoua, Cameroon.
Andrea M McCollumDivision of High Consequence Pathogens and Pathology, US Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0002-9136-818X
Centers for Disease Control and Prevention · USMetabiota (Cameroon) · CMUniversité de Yaoundé I · CMMinistry of Livestock, Fisheries and Animal Industries · CMNational Public Health Laboratory · NPRoslin Institute · GBUniversity of Douala · CM

Funding

Defense Threat Reduction AgencyIntramural CDC HHS CC999999United States Agency for International DevelopmentUnited States Department of Defense
6 · The paper itself

Abstract

Monkeypox virus (MPXV) is a reemerging virus of global concern. An outbreak of clade I MPXV affected 20 captive chimpanzees in Cameroon in 2016. We describe the epidemiology, virology, phylogenetics, and clinical progression of this outbreak. Clinical signs included exanthema, facial swelling, perilaryngeal swelling, and eschar. Mpox can be lethal in captive chimpanzees, with death likely resulting from respiratory complications. We advise avoiding anesthesia in animals with respiratory signs to reduce the likelihood of death. This outbreak presented a risk to animal care staff. There is a need for increased awareness and a One Health approach to preparation for outbreaks in wildlife rescue centers in primate range states where MPXV occurs. Control measures should include quarantining affected animals, limiting human contacts, surveillance of humans and animals, use of personal protective equipment, and regular decontamination of enclosures.

Indexed as

Monkeypox virusPan troglodytesAnimalsAnimals, WildCameroonDisease OutbreaksHumansMpox, MonkeypoxepidemiologympoxOne Healthoutbreakzoonosis

Identifiers

PMID38164967
PMCPMC11949251
OpenAlexW4390500188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.