ArticleHypertension (Dallas, Tex. : 1979)2024
Blood Pressure Trajectories and Outcomes After Endovascular Thrombectomy for Acute Ischemic Stroke.
Article in Hypertension (Dallas, Tex. : 1979), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.
- 2025 update to European Stroke Organisation (ESO) guideline on blood pressure management in acute ischaemic stroke and intracerebral haemorrhage.European stroke journal · 2026Guideline
- Baseline systolic blood pressure and efficacy of dual antiplatelet in acute ischaemic stroke.Stroke and vascular neurology · 2025Trial
- Mean arterial pressure and pulse pressure trajectories and clinical outcomes after acute ischemic stroke.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Blood Pressure Variability in Acute Ischemic Stroke: Current Evidence, Measurement Challenges, and Future Directions.Journal of clinical hypertension (Greenwich, Conn.) · 2026Review
- Blood pressure management in patients receiving rescue stenting after failed endovascular treatment in large vessel occlusion acute ischaemic stroke: a multicentre registry.European stroke journal · 2026Article
- Identification of vital sign trajectory phenotypes and treatment response heterogeneity in critically ill patients with ischemic stroke: A multicenter study with external validation.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Article
- Long-term systolic blood pressure and cardiovascular risks among patients with ischemic stroke: a register-based cohort study.Journal of global health · 2025Article
- Blood Pressure Management Pre- and Post-Reperfusion in Acute Ischemic Stroke: Evidence and Insights from Recent Studies.Current neurology and neuroscience reports · 2025Review
- Association Between Estimated Pulse Wave Velocity and Endovascular Thrombectomy Outcome: A Secondary Analysis of the OPTIMAL-BP Trial.Stroke (Hoboken, N.J.) · 2025Article
- Impact of Systolic Blood Pressure Trajectories and Variability on Unexplained Early Neurological Deterioration Post-Endovascular Treatment in Acute Ischemic Stroke Patients.Journal of clinical hypertension (Greenwich, Conn.) · 2025Observational
- Blood pressure management after endovascular thrombectomy: Insights of recent randomized controlled trials.CNS neuroscience & therapeutics · 2024Review
Corrections and comments
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Authors and funding
25 authors at 17 institutions in 8 countries.
Funding
Abstract
backgroundData on systolic blood pressure (SBP) trajectories in the first 24 hours after endovascular thrombectomy (EVT) in acute ischemic stroke are limited. We sought to identify these trajectories and their relationship to outcomes.
methodsWe combined individual-level data from 5 studies of patients with acute ischemic stroke who underwent EVT and had individual blood pressure values after the end of the procedure. We used group-based trajectory analysis to identify the number and shape of SBP trajectories post-EVT. We used mixed effects regression models to identify associations between trajectory groups and outcomes adjusting for potential confounders and reported the respective adjusted odds ratios (aORs) and common odds ratios.
resultsThere were 2640 total patients with acute ischemic stroke included in the analysis. The most parsimonious model identified 4 distinct SBP trajectories, that is, general directional patterns after repeated SBP measurements: high, moderate-high, moderate, and low. Patients in the higher blood pressure trajectory groups were older, had a higher prevalence of vascular risk factors, presented with more severe stroke syndromes, and were less likely to achieve successful recanalization after the EVT. In the adjusted analyses, only patients in the high-SBP trajectory were found to have significantly higher odds of early neurological deterioration (aOR, 1.84 [95% CI, 1.20-2.82]), intracranial hemorrhage (aOR, 1.84 [95% CI, 1.31-2.59]), mortality (aOR, 1.75 [95% CI, 1.21-2.53), death or disability (aOR, 1.63 [95% CI, 1.15-2.31]), and worse functional outcomes (adjusted common odds ratio,1.92 [95% CI, 1.47-2.50]).
conclusionsPatients follow distinct SBP trajectories in the first 24 hours after an EVT. Persistently elevated SBP after the procedure is associated with unfavorable short-term and long-term outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.