Evidence map›Paper›PMID 38164715›Full record

ArticleEmerging microbes & infections2024

Capsid protein mediated evasion of IRAK1-dependent signalling is essential to Sindbis virus neuroinvasion and virulence in mice.

V Douglas Landers, Milton Thomas, Cierra M Isom, Deepa Karki, Kevin J Sokoloski

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Emerging microbes & infections, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

V Douglas LandersDepartment of Microbiology and Immunology, School of Medicine, University of Louisville, Louisville, KY, USA.
Milton ThomasDepartment of Microbiology and Immunology, School of Medicine, University of Louisville, Louisville, KY, USA.
Cierra M IsomDepartment of Microbiology and Immunology, School of Medicine, University of Louisville, Louisville, KY, USA.
Deepa KarkiDepartment of Microbiology and Immunology, School of Medicine, University of Louisville, Louisville, KY, USA.
Kevin J SokoloskiDepartment of Microbiology and Immunology, School of Medicine, University of Louisville, Louisville, KY, USA.

Funding

WKU Lead Faculty AwardP20GM103436 · NIGMS · UNIVERSITY OF LOUISVILLE · PI ERIC C ROUCHKA · 2012 to 2026
$60.1M
Understanding the Host-Microbiome-Therapeutic Triad: Implications for Designing Alternative IntravaginalP20GM125504 · NIGMS · UNIVERSITY OF LOUISVILLE · PI Shirin Ghods · 2018 to 2026
$24.4M
PILOT PROJECT PROGRAMP30GM106396 · NIGMS · UNIVERSITY OF LOUISVILLE · PI MILLER, DONALD M. · 2013 to 2017
$5.4M
Comprehensive Definition of the Critical Role(s) of the Alphaviral Noncapped Genomic RNAs to Infection and PathogenesisR01AI153275 · NIAID · UNIVERSITY OF LOUISVILLE · PI SOKOLOSKI, KEVIN JOSEPH · 2020 to 2024
$2.3M
Inflammation and Pathogenesis Training ProgramT32AI132146 · NIAID · UNIVERSITY OF LOUISVILLE · PI LAMONT, RICHARD J, MITCHELL, THOMAS C. · 2018 to 2022
$640k
NIAID NIH HHS R01 AI153275NIAID NIH HHS T32 AI132146NIGMS NIH HHS P20 GM103436NIGMS NIH HHS P20 GM125504NIGMS NIH HHS P30 GM106396
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Chikungunya virusSindbis VirusAnimalsCapsid ProteinsMiceVirulenceVirus ReplicationCapsid ProteinsAlphaviruscapsidinnate immunityIRAK1neurovirulencepathogenesisSindbis virus

Identifiers

PMID38164715
PMCPMC10773654

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.