Evidence map›Paper›PMID 38164463›Full record

ReviewJournal of multidisciplinary healthcare2023

Evaluating the Aspects of Quality of Life in Individuals with Substance Use Disorder: A Systematic Review Based on the WHOQOL Questionnaire.

Melania Lavinia Bratu, Dorel Sandesc, Teodora Anghel, Raluca Tudor, Luai Shaaban, Ayesha Ali, Ana-Olivia Toma, Felix Bratosin, Izabela Turcu, Andrei Gantsa and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of multidisciplinary healthcare, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Substance Use Disorder Treatment Outcomes: Methodological Overview of Metrics and Criteria.International journal of methods in psychiatric research · 2025
    Pooled it
  3. Article
  4. Effectiveness of Naltrexone and Baclofen Combination in Reducing Craving among Patients with Alcohol Dependence: An Open-label Trial.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2026
    Article
  5. Drug Use-related Problems Are Associated with Poorer Health-related Quality of Life: A Community Study of Korean Adults.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Quality of life measures in treatment for active substance misuse: a scoping review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  10. Examining quality of life by recovery status among college students with a history of substance use.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  11. Article
  12. Impact of a minimal monitoring HCV treatment approach on Health-Related Quality of Life.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 5 countries.

Melania Lavinia BratuCenter for Neuropsychology and Behavioral Medicine, Department of Psychology, Faculty of General Medicine, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
Dorel SandescDepartment of Anesthesia and Intensive Care, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
Teodora AnghelCenter for Neuropsychology and Behavioral Medicine, Department of Psychology, Faculty of General Medicine, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
Raluca TudorSecond Discipline of Neurology, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.ORCID 0000-0002-1971-6901
Luai ShaabanFaculty of General Medicine, Baskent University, Ankara, Turkey.ORCID 0000-0002-2402-4045
Ayesha AliBhaskar Medical College, Hyderabad, Telangana State, India.
Ana-Olivia TomaDiscipline of Dermatology, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
Felix BratosinDoctoral School, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.ORCID 0000-0003-4711-4315
Izabela TurcuIuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Andrei GantsaVolgograd State Medical University, Volgograd, Russia.
Roxana Manuela FericeanDoctoral School, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
Mariana BondrescuDoctoral School, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.ORCID 0000-0003-0852-3503
Paula Irina BarataDepartment of Physiology, Faculty of Medicine, "Vasile Goldis" Western University, Arad, Romania.
Victor Babeș University of Medicine and Pharmacy Timișoara · ROBaşkent University · TRGandhi Medical College & Hospital · INIuliu Hațieganu University of Medicine and Pharmacy · ROVolgograd State Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Substance Use Disorder (SUD) has become a significant public health concern and it profoundly impacts an individual's quality of life (QOL). This systematic review aimed to assess the QOL among patients with SUD, and to understand the differential impact of SUD on physical, mental, social, and environmental QOL domains, considering a variety of substances and identifying key factors that influence these outcomes. A comprehensive search was conducted in PubMed, Web of Science, Cochrane, and Scopus in January 2023, covering literature published until December 2022. The QOL was assessed using the World Health Organization Quality of Life (WHOQOL) instrument and the brief version of the WHOQOL, identifying the same four domains of QOL (physical, mental, social, and environmental). A total of 19 studies were selected for inclusion in the systematic review, based on individuals' polysubstance use, and excluding those using only nicotine or alcohol. The analysis included 6079 patients, with only 40.3% women, and a mean age of 36.6 years. The substances most commonly involved in SUD were cocaine (47.1%), alcohol (46.3%), and amphetamine (43.6%), considering most individuals being polysubstance users. The highest variability in QOL scores was observed in the physical domain. Mental disorders were reported in 68.3% of the patients, while long-term use of drugs, criminal history, unemployment, and low levels of education were identified as significant predictors for lower QOL by some of the studies. Similarly, sleep problems and teeth decay were also identified as significant worsening factors for QOL. This systematic review highlights that the WHOQOL survey is widely accepted and applicable for individuals with SUD worldwide. The results suggest a substantial negative impact of SUD on the QOL of affected individuals. The findings underscore the need for comprehensive interventions to address the physical, psychological, social, and environmental dimensions of QOL among individuals with SUD.

Indexed as

quality of lifesubstance abusesubstance addiction

Identifiers

PMID38164463
PMCPMC10758186
OpenAlexW4390349395

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.