Evidence map›Paper›PMID 38164394›Full record

ArticleFrontiers in veterinary science2023

A widespread picornavirus affects the hemocytes of the noble pen shell (

Francesca Carella, Patricia Prado, Gionata De Vico, Dušan Palić, Grazia Villari, José Rafael García-March, José Tena-Medialdea, Emilio Cortés Melendreras, Francisca Giménez-Casalduero, Marco Sigovini and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Animals : an open access journal from MDPI · 2025
    Review
  4. Article
  5. Handling of the BivalveEcology and evolution · 2024
    Article
  6. Ecology and evolution · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Francesca CarellaDepartment of Biology, University of Naples Federico II, Naples, Italy.
Patricia PradoInstitute of Agrifood Research and Technology (IRTA)-Sant Carles de la Ràpita, Tarragona, Spain.
Gionata De VicoDepartment of Biology, University of Naples Federico II, Naples, Italy.
Dušan PalićChair for Fish Diseases and Fisheries Biology, Faculty of Veterinary Medicine, Ludwig-Maximilians-University Munich, Munich, Germany.
Grazia VillariDepartment of Biology, University of Naples Federico II, Naples, Italy.
José Rafael García-MarchInstituto de Investigación en Medio Ambiente y Ciencia Marina, Universidad Católica de Valencia, Calpe, Spain.
José Tena-MedialdeaInstituto de Investigación en Medio Ambiente y Ciencia Marina, Universidad Católica de Valencia, Calpe, Spain.
Emilio Cortés MelendrerasMurcia University Aquarium, University of Murcia, Murcia, Spain.
Francisca Giménez-CasaldueroDepartment of Marine Science and Applied Biology, Research Marine Centre in Santa Pola (CIMAR), University of Alicante, Alicante, Spain.
Marco SigoviniConsiglio Nazionale delle Ricerche, Istituto di Scienze Marine, Venice, Italy.
Serena AcetoDepartment of Biology, University of Naples Federico II, Naples, Italy.
University of Naples Federico II · ITValencia Catholic University Saint Vincent Martyr · ESInstitute for Research and Technology in Food and Agriculture · ESInstitute of Marine Science · ITLudwig-Maximilians-Universität München · DEUniversidad de Murcia · ESUniversity of Alicante · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The widespread mass mortality of the noble pen shell ( Methods: We sampled Results and discussion: In 100% of our samples, ultrastructure revealed the presence of a virus (20 nm diameter) capable of replicating within granulocytes and hyalinocytes, leading to the accumulation of complex vesicles of different dimensions within the cytoplasm. As the PV infection progressed, dead hemocytes, infectious exosomes, and budding of extracellular vesicles were visible, along with endocytic vesicles entering other cells. The THC (total hemocyte count) values observed in both captive (eight animals) (3.5 × 10

Indexed as

immunosuppressionmass mortalitynoble pen shellRNA virusRT-PCR

Identifiers

PMID38164394
PMCPMC10758234
OpenAlexW4389883617

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.