Evidence map›Paper›PMID 38164347›Full record

ReviewInternational journal of medical sciences2024

Novel Insights into Prokineticin 1 Role in Pregnancy-related Diseases.

Xi-Xi Cheng, Ming-Qing Li, Ting Peng

Open access · goldAbstract readReview
In one paragraph

Review in International journal of medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Xi-Xi ChengShanghai Changning Maternity & Infant Health Hospital, China.
Ming-Qing LiNHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Hospital of Obstetrics and Gynecology, Fudan University, Shanghai 200080, China.
Ting PengShanghai Changning Maternity & Infant Health Hospital, China.
Obstetrics and Gynecology Hospital of Fudan University · CNShanghai Changning Maternity and Infant Health Hospital · CNShanghai Institute of Planned Parenthood Research · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prokineticin 1 (PROK1) is a secreted protein involved in a range of physiological activities such as cell proliferation, migration, angiogenesis, and neuronal cell proliferation. Emerging evidences show that PROK1/PROK receptors (PROKRs) are expressed by trophoblasts, and decidual stroma cells at the maternal-fetal interface. PROK1 plays a critical role in successful pregnancy establishment by regulating the decidualization, implantation and placental development. Dysregulation of prokineticin signaling has been described in certain pathological states associated with pregnancy, including pre-eclampsia, recurrent miscarriage and fetal growth restriction. In this review, the expression and pleiotropic roles of PROK1 under physiological and pathological pregnancy conditions are discussed.

Indexed as

Gastrointestinal HormonesPre-EclampsiaVascular Endothelial Growth Factor, Endocrine-Gland-DerivedFemaleHumansPlacentaPregnancySignal TransductionTrophoblastsGastrointestinal HormonesPROK1 protein, humanVascular Endothelial Growth Factor, Endocrine-Gland-Derivedangiogenesisfetal growth restrictionmaternal-fetal interfacepreeclampsiaprokineticin1recurrent miscarriage

Identifiers

PMID38164347
PMCPMC10750342
OpenAlexW4388699891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.