Evidence map›Paper›PMID 38164170›Full record

ArticleInternational journal of biological sciences2024

G3BP1 Interact with JAK2 mRNA to Promote the Malignant Progression of Nasopharyngeal Carcinoma via Activating JAK2/STAT3 Signaling Pathway.

Yuting Zhan, Weiyuan Wang, Haihua Wang, Yue Xu, Yuting Zhang, Yue Ning, Hongmei Zheng, Jiadi Luo, Yang Yang, Hongjing Zang and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of biological sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Yuting ZhanDepartment of Pathology, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Weiyuan WangDepartment of Pathology, Xiangya Hospital of Central South University, Changsha, Hunan, China.
Haihua WangDepartment of Pathology, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yue XuDepartment of Pathology, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yuting ZhangDepartment of Pathology, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yue NingDepartment of Pathology, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Hongmei ZhengDepartment of Pathology, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Jiadi LuoDepartment of Pathology, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yang YangDepartment of Pathology, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Hongjing ZangDepartment of Pathology, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Ming ZhouCancer Research Institute and School of Basic Medicine Sciences, Central South University, Changsha, Hunan, China.
Songqing FanDepartment of Pathology, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Central South University · CNSecond Xiangya Hospital of Central South University · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ras-GTPase-activating protein (GAP)-binding protein 1 (G3BP1) is an RNA-binding protein implicated in various malignancies. However, its role in nasopharyngeal carcinoma (NPC) remains elusive. This study elucidates the potential regulation mechanisms of G3BP1 and its significance in NPC advancement. Through knockdown and overexpression approaches, we validate G3BP1's oncogenic role by promoting proliferation, migration, and invasion

Indexed as

DNA HelicasesNasopharyngeal NeoplasmsCell Line, TumorCell ProliferationHumansJanus Kinase 2Nasopharyngeal CarcinomaPoly-ADP-Ribose Binding ProteinsRNA HelicasesRNA Recognition Motif ProteinsSignal TransductionSTAT3 Transcription FactorDNA HelicasesG3BP1 protein, humanJAK2 protein, humanJanus Kinase 2Poly-ADP-Ribose Binding ProteinsRNA HelicasesRNA Recognition Motif ProteinsSTAT3 protein, humanSTAT3 Transcription FactorG3BP1JAK2/STAT3 signaling pathwaymalignant progressionRNA binding protein

Identifiers

PMID38164170
PMCPMC10750281
OpenAlexW4388699677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.