Evidence map›Paper›PMID 38164108›Full record

ArticleCancer medicine2024

Survival in oral and pharyngeal cancers is catching up with laryngeal cancer in the NORDIC countries through a half century.

Frantisek Zitricky, Anni I Koskinen, Otto Hemminki, Asta Försti, Akseli Hemminki, Kari Hemminki

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Article in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Radiation-induced malignancies from simultaneous integrated boost-VMAT for oropharyngeal cancer delivered with four different fractionation schemes.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2026
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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Frantisek ZitrickyFaculty of Medicine and Biomedical Center in Pilsen, Charles University in Prague, Pilsen, Czech Republic.ORCID 0000-0001-7600-7143
Anni I KoskinenDepartment of Otorhinolaryngology- Head and Neck Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Otto HemminkiDepartment of Urology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Asta FörstiHopp Children's Cancer Center (KiTZ), Heidelberg, Germany.
Akseli HemminkiCancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.ORCID 0000-0001-7103-8530
Kari HemminkiFaculty of Medicine and Biomedical Center in Pilsen, Charles University in Prague, Pilsen, Czech Republic.ORCID 0000-0002-2769-3316

Funding

European Union's Horizon 2020, grant no. 856620 (Chaperon)
6 · The paper itself

Abstract

backgroundCancers of the head and neck (HN) are heterogeneous tumors with incidence rates varying globally. In Northern Europe oral and oropharyngeal cancers are the most common individual types. Survival for HN varies by individual tumor type but for most of them survival trends are not well known over extended periods of time.

methodsData for a retrospective survival study were obtained for Danish, Finnish, Norwegian, and Swedish patients from the NORDCAN database from 1971 to 2020. Relative 1- and 5-year survival rates and 5/1-year conditional survival for years 2-5 were calculated.

resultsBoth 1- and 5-year survival improved for all HN cancers but only marginally for laryngeal cancer. For the other cancers a 50-year increase in 5-year survival was about 30% units for nasopharyngeal and oropharyngeal cancers, 20% units for oral cancer and somewhat less for hypopharyngeal cancer.

conclusions5-year survival reached about 65% for all HN cancers, except for hypopharyngeal cancer (30%). Human papilloma virus infection is becoming a dominant risk factor for the rapidly increasing oropharyngeal cancer, the prevention of which needs to emphasize oral sex as a route of infection.

Indexed as

Laryngeal NeoplasmsPharyngeal NeoplasmsAgedFemaleHumansIncidenceMaleMiddle AgedMouth NeoplasmsRetrospective StudiesRisk FactorsScandinavian and Nordic CountriesSurvival Rateconditional survivalhuman papilloma virusoral cancerpharyngeal cancer

Identifiers

PMID38164108
PMCPMC10807619

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.