Evidence map›Paper›PMID 38164037›Full record

ArticleThe world journal of men's health2024

Patient Satisfaction with Oral Testosterone Undecanoate in Men Who Received Prior Testosterone Therapy: An Open-Label, Single-Center Clinical Trial.

Marco-Jose Rivero, Rohit Reddy, Akhil Muthigi, Raghuram Reddy, Sunwoo Han, Isildinha M Reis, Mehul Patel, Ranjith Ramasamy

Abstract read
In one paragraph

Article in The world journal of men's health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marco-Jose RiveroDesai Sethi Urology Institute, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID https://orcid.org/0000-0002-0451-7192
Rohit ReddyDesai Sethi Urology Institute, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID https://orcid.org/0000-0003-1032-6656
Akhil MuthigiDesai Sethi Urology Institute, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID https://orcid.org/0000-0001-5885-3653
Raghuram ReddyHerbert Wertheim College of Medicine, Florida International University, Miami, FL, USA.ORCID https://orcid.org/0000-0002-7636-392X
Sunwoo HanBiostatistics and Bioinformatics Shared Resource, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID https://orcid.org/0000-0001-6874-2471
Isildinha M ReisBiostatistics and Bioinformatics Shared Resource, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID https://orcid.org/0000-0002-7695-8771
Mehul PatelDesai Sethi Urology Institute, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID https://orcid.org/0000-0002-2304-3324
Ranjith RamasamyDesai Sethi Urology Institute, University of Miami Miller School of Medicine, Miami, FL, USA. ramasamy@miami.edu.ORCID https://orcid.org/0000-0003-1387-7904

Funding

Clarus Therapeutics GR017931
6 · The paper itself

Abstract

purposeTo evaluate patient satisfaction and symptom control in hypogonadal men transitioning from other testosterone therapies to oral testosterone undecanoate (TU). MATERIALS AND

methodsIn this open-label clinical trial, men aged 18 to 75 years with hypogonadism were switched to oral TU after a sufficient washout of previous testosterone therapies. Treatment satisfaction and symptom control were primarily measured using the 9-item Treatment Satisfaction Questionnaire for Medication (TSQM-9) and quantitative androgen deficiency in aging males (qADAM) questionnaires, respectively. Secondary outcomes included changes in serum testosterone (T), estradiol (E2), hematocrit (HCT), and prostate-specific antigen (PSA) levels.

resultsForty-one men participated, with significant improvements in all TSQM-9 scores observed over 6 months. Symptom control as measured by qADAM remained consistent. There was a significant increase in serum T and E2 levels, but HCT and PSA levels remained stable.

conclusionsSwitching to oral TU from other testosterone therapies is associated with increased patient satisfaction and stable hypogonadal symptom control.

Indexed as

Clinical trialHypogonadismPatient satisfactionTestosterone

Identifiers

PMID38164037
PMCPMC11439809

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.