Evidence map›Paper›PMID 38163170›Full record

ArticleHeliyon2024

The oligodontia phenotype in a X-linked hypohidrotic ectodermal dysplasia patient with a novel

Yi Wu, Jing Sun, Caiqi Zhang, Siyuan Ma, Yiting Liu, Xiaoshan Wu, Qingping Gao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Yi WuThe Stomatology Center of Xiangya Hospital, Academician Workstation for Oral & Maxillofacial Regenerative Medicine, Research Center of Oral and Maxillofacial Development and Regeneration, National Clinical Research Center for Geriatric Diseases, Central South Universtiy, Changsha, Hunan Province, China.
Jing SunThe Stomatology Center of Xiangya Hospital, Academician Workstation for Oral & Maxillofacial Regenerative Medicine, Research Center of Oral and Maxillofacial Development and Regeneration, National Clinical Research Center for Geriatric Diseases, Central South Universtiy, Changsha, Hunan Province, China.
Caiqi ZhangThe Stomatology Center of Xiangya Hospital, Academician Workstation for Oral & Maxillofacial Regenerative Medicine, Research Center of Oral and Maxillofacial Development and Regeneration, National Clinical Research Center for Geriatric Diseases, Central South Universtiy, Changsha, Hunan Province, China.
Siyuan MaThe Stomatology Center of Xiangya Hospital, Academician Workstation for Oral & Maxillofacial Regenerative Medicine, Research Center of Oral and Maxillofacial Development and Regeneration, National Clinical Research Center for Geriatric Diseases, Central South Universtiy, Changsha, Hunan Province, China.
Yiting LiuThe Stomatology Center of Xiangya Hospital, Academician Workstation for Oral & Maxillofacial Regenerative Medicine, Research Center of Oral and Maxillofacial Development and Regeneration, National Clinical Research Center for Geriatric Diseases, Central South Universtiy, Changsha, Hunan Province, China.
Xiaoshan WuThe Stomatology Center of Xiangya Hospital, Academician Workstation for Oral & Maxillofacial Regenerative Medicine, Research Center of Oral and Maxillofacial Development and Regeneration, National Clinical Research Center for Geriatric Diseases, Central South Universtiy, Changsha, Hunan Province, China.
Qingping GaoThe Stomatology Center of Xiangya Hospital, Academician Workstation for Oral & Maxillofacial Regenerative Medicine, Research Center of Oral and Maxillofacial Development and Regeneration, National Clinical Research Center for Geriatric Diseases, Central South Universtiy, Changsha, Hunan Province, China.
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To analyse the pathogenic genes in a patient with hypohidrotic ectodermal dysplasia (HED) and explore the relationship between pathogenic genes and the oligodontia phenotype. Methods: Clinical data and peripheral blood were collected from a patient with HED. Pathogenic genes were analysed by whole-exon sequencing (WES) and verified by Singer sequencing. The secondary and tertiary structures of the variant proteins were predicted to analyse their toxicity. Results: The patient exhibited a severe oligodontia phenotype, wherein only two deciduous canines were left in the upper jaw. WES revealed a hemizygous Conclusion: The patient demonstrated a more severe oligodontia phenotype when compared with the other patients caused by the

Indexed as

EDAEVC2Hypohidrotic ectodermal dysplasiaOligodontia

Identifiers

PMID38163170
PMCPMC10756976
OpenAlexW4389372041

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.