Evidence map›Paper›PMID 38162898›Full record

ArticleBrain communications2024

Cerebral perfusion in post-stroke aphasia and its relationship to residual language abilities.

Maria V Ivanova, Ioannis Pappas, Ben Inglis, Alexis L Pracar, Timothy J Herron, Juliana V Baldo, Andrew S Kayser, Mark D'Esposito, Nina F Dronkers

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Observational
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Maria V IvanovaDepartment of Psychology, University of California, Berkeley, CA 94720, USA.
Ioannis PappasStevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, CA 90033, USA.
Ben InglisHenry H. Wheeler, Jr. Brain Imaging Center, University of California, Berkeley, CA 94720, USA.
Alexis L PracarDepartment of Psychology, University of California, Berkeley, CA 94720, USA.
Timothy J HerronResearch Service, VA Northern California Health Care System, Martinez, CA 94553, USA.ORCID https://orcid.org/0000-0002-4297-014X
Juliana V BaldoResearch Service, VA Northern California Health Care System, Martinez, CA 94553, USA.
Andrew S KayserDivision of Neurology, San Francisco VA Health Care System, San Francisco, CA 94121, USA.
Mark D'EspositoDepartment of Psychology, University of California, Berkeley, CA 94720, USA.
Nina F DronkersDepartment of Psychology, University of California, Berkeley, CA 94720, USA.
VA Northern California Health Care System · USImaging Center · USUniversity of California, Berkeley · USUniversity of California, Davis · USUniversity of California, San Francisco · USUniversity of Southern California · US

Funding

TDP-43 Loss-of-Function: Biology to BiomarkersP01AG019724 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Jennifer Merrilees · 2002 to 2026
$67.2M
USCADRC Diversity Supplement PachicanoP30AG066530 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HELENA Chang CHUI · 2020 to 2026
$27.8M
Working Memory and Prefrontal CortexR01MH063901 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI D'ESPOSITO, MARK · 2001 to 2022
$7.6M
Primary Progressive Aphasia: Cognition, Anatomy and ProgressionRF1NS050915 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GORNO TEMPINI, MARIA LUISA · 2022 to 2022
$4.7M
Neural Mechanisms of Language Production Decline in Primary Progressive AphasiaR01DC016345 · NIDCD · UNIVERSITY OF CALIFORNIA BERKELEY · PI DRONKERS, NINA F. · 2017 to 2022
$2.8M
Exercising language: Behavioral and neurophysiological changes after high-intensity exercise training in post-stroke aphasia.R56DC020700 · NIDCD · UNIVERSITY OF CALIFORNIA BERKELEY · PI IVANOVA, MARIA V. · 2023 to 2023
$713k
Neural Mechanisms of Song vs Speech Production: Insights from Aphasia and Intracranial RecordingR21DC021042 · NIDCD · UNIVERSITY OF CALIFORNIA BERKELEY · PI DRONKERS, NINA F. · 2023 to 2024
$417k
Developing Behavioral and Neuroimaging Predictors of Stroke RecoveryI01RX002783 · VA · VA NORTHERN CALIFORNIA HEALTH CARE SYS · PI D'ESPOSITO, MARK · 2019 to 2023
–
NIA NIH HHS P01 AG019724NIA NIH HHS P30 AG066530NIDCD NIH HHS R01 DC016345NIDCD NIH HHS R21 DC021042NIDCD NIH HHS R56 DC020700NIMH NIH HHS R01 MH063901NINDS NIH HHS RF1 NS050915RRD VA I01 RX002783
6 · The paper itself

Abstract

Stroke alters blood flow to the brain resulting in damaged tissue and cell death. Moreover, the disruption of cerebral blood flow (perfusion) can be observed in areas surrounding and distal to the lesion. These structurally preserved but suboptimally perfused regions may also affect recovery. Thus, to better understand aphasia recovery, the relationship between cerebral perfusion and language needs to be systematically examined. In the current study, we aimed to evaluate (i) how stroke affects perfusion outside of lesioned areas in chronic aphasia and (ii) how perfusion in specific cortical areas and perilesional tissue relates to language outcomes in aphasia. We analysed perfusion data from a large sample of participants with chronic aphasia due to left hemisphere stroke (

Indexed as

aphasialanguageperfusionperilesionaltemporoparietal areas

Identifiers

PMID38162898
PMCPMC10757451
OpenAlexW4387358144

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.