Evidence map›Paper›PMID 38162862›Full record

ReviewJGH open : an open access journal of gastroenterology and hepatology2023

Gastric adenocarcinoma of the fundic gland type: A review of the literature.

Zhiyong Zhai, Wei Hu, Zhaoyu Huang, Zemin Chen, Sicun Lu, Wei Gong

Open access · goldAbstract readReview
In one paragraph

Review in JGH open : an open access journal of gastroenterology and hepatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Feasibility study of cap-assisted endoscopic mucosal resection for gastric adenocarcinoma of fundic gland type.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
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  4. Review
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zhiyong ZhaiDepartment of Gastroenterology, Shenzhen Hospital Southern Medical University Shenzhen China.ORCID https://orcid.org/0000-0003-2198-8137
Wei HuDepartment of Gastroenterology, Shenzhen Hospital Southern Medical University Shenzhen China.
Zhaoyu HuangDepartment of Gastroenterology, Shenzhen Hospital Southern Medical University Shenzhen China.
Zemin ChenDepartment of Gastroenterology, Shenzhen Hospital Southern Medical University Shenzhen China.
Sicun LuDepartment of Gastroenterology, Shenzhen Hospital Southern Medical University Shenzhen China.
Wei GongDepartment of Gastroenterology, Shenzhen Hospital Southern Medical University Shenzhen China.
Third Affiliated Hospital of Southern Medical University · CNSouthern Medical University Shenzhen Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Gastric adenocarcinoma of the fundic gland type (GA-FG) is a newly described tumor entity but lacking consensus. This review summarizes the key features and controversies regarding this uncommon neoplasm. Methods: We reviewed studies on GA-FG published in English from 2007 to 2021. Results: We found that 327 cases (340 lesions) have been reported. GA-FG lesions originate from deep layers of the gastric mucosa, with the following characteristics on conventional white-light endoscopy examination. These lesions, macroscopically identified as submucosal tumor-like 0-IIa, tend to have a whitish discoloration without inflammation, atrophy, or intestinal metaplasia in the background mucosa. Tumors located in the upper third of the stomach are usually solitary, with an average size <10 mm. Contrastingly, magnifying endoscopy with narrow-band imaging mostly shows the absence of any demarcation line, with a regular microvascular pattern and regular microsurface pattern. GA-FGs are covered with normal foveolar epithelium, forming a so-called endless glands pattern in the deeper region, which are mainly composed of chief cells or parietal cells. Most tumors exhibit submucosal invasion, but lymphovascular invasion and nodal metastasis are rare. Regarding the treatment of GA-FG, endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR) are effective treatment methods. Conclusions: GA-FG is a rare tumor that typically follows a benign course. This neoplasm has distinct endoscopic and pathological features and could be treated by ESD or EMR.

Indexed as

chief cellendoscopic mucosal resectionendoscopic submucosal dissectiongastric adenocarcinoma of the fundic gland typemagnifying endoscopy with narrow‐band imaging

Identifiers

PMID38162862
PMCPMC10757499
OpenAlexW4389205136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.