Evidence map›Paper›PMID 38162858›Full record

ArticleJGH open : an open access journal of gastroenterology and hepatology2023

Association of gut microbiota with portal vein pressure in patients with liver cirrhosis undergoing living donor liver transplantation.

Katsuya Toshida, Shinji Itoh, Yukiko Kosai-Fujimoto, Takuma Ishikawa, Yuki Nakayama, Yuriko Tsutsui, Norifumi Iseda, Takuma Izumi, Yuki Bekki, Shohei Yoshiya and 3 more

Open access · goldAbstract read
In one paragraph

Article in JGH open : an open access journal of gastroenterology and hepatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Katsuya ToshidaDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.ORCID https://orcid.org/0000-0002-4158-3287
Shinji ItohDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.ORCID https://orcid.org/0000-0003-0382-2520
Yukiko Kosai-FujimotoDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Takuma IshikawaDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Yuki NakayamaDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Yuriko TsutsuiDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Norifumi IsedaDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Takuma IzumiDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Yuki BekkiDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Shohei YoshiyaDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Takeo ToshimaDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.ORCID https://orcid.org/0000-0003-4019-8288
Makoto NakamutaDepartment of Gastroenterology, Kyushu Medical Center National Hospital Organization Fukuoka Japan.
Tomoharu YoshizumiDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Kyushu University · JPNational Kyushu Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Many recent studies have shown a relationship between various systemic diseases and the gut microbiota (GM), with the gut-liver axis receiving particular attention. In contrast, no report has comprehensively shown the effects of GM on the pathophysiology of patients undergoing living donor liver transplantation (LDLT). Method: We enrolled 16 recipients who underwent LDLT for liver cirrhosis, and 17 donors constituted the reference group. We examined the differences in GM between recipients and donors. We also examined the relationships between GM, short-chain fatty acids, and portal vein pressure (PVP) in recipients. Results: There was no significant difference in alpha-diversity between the recipients and donors, but there was variation in beta-diversity among the recipients. The abundance of the phylum Bacteroidetes was significantly higher in recipients than in donors ( Conclusion: Our findings suggest relationships between fecal Bacteroidetes levels, propionic acid concentrations, and PVP in patients with liver cirrhosis undergoing LDLT.

Indexed as

gut microbiotaliving donor liver transplantationportal vein pressurepropionate

Identifiers

PMID38162858
PMCPMC10757484
OpenAlexW4389504035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.