ArticleJournal of electrical bioimpedance2023
Detection of physiological concentrations of GABA using dielectric spectroscopy - A pilot study.
Article in Journal of electrical bioimpedance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- Comparison of Vegetable Waste Byproducts of Selected Cultivars of Foeniculum vulgare Mill. by an Integrated LC-(HR)MS andPhytochemical analysis : PCA · 2025Article
- Using neuromorphic computing in prediction of GABA concentration - a pilot study.Journal of electrical bioimpedance · 2025Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
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Abstract
Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter that is present at a relatively low level throughout the normal adult human brain. Abnormal GABA levels are found in people with neurodegenerative disorders such as Parkinson's disease, epilepsy, schizophrenia, depression, and others. Being able to measure the GABA concentration would be beneficial for patient groups with fluctuating GABA levels for better diagnosis and treatment. In this study, we explore the feasibility of using dielectric relaxation spectroscopy for the detection of GABA concentrations within a physiological range, with the perspective of miniaturization and use during implantation. Utilizing machine learning techniques, we were able to differentiate GABA concentrations down to 5 μm. This work investigates a novel use of dielectric relaxation spectroscopy, to assess if physiological GABA concentrations can be detected through permittivity measurements.
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