Evidence map›Paper›PMID 38162683›Full record

ArticleFrontiers in genetics2023

Whole genome sequence analysis of apparent treatment resistant hypertension status in participants from the Trans-Omics for Precision Medicine program.

Nicole D Armstrong, Vinodh Srinivasasainagendra, Farah Ammous, Themistocles L Assimes, Amber L Beitelshees, Jennifer Brody, Brian E Cade, Yii-Der Ida Chen, Han Chen, Paul S de Vries and 34 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Pharmacogenetics: Opportunities for theAnnual review of pharmacology and toxicology · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

44 authors at 20 institutions in 2 countries.

Nicole D ArmstrongDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, United States.
Vinodh SrinivasasainagendraDepartment of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, United States.
Farah AmmousDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, United States.
Themistocles L AssimesDivision of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, United States.
Amber L BeitelsheesDivision of Endocrinology, Diabetes, and Nutrition, Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, United States.
Jennifer BrodyCardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, United States.
Brian E CadeDivision of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States.
Yii-Der Ida ChenThe Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, United States.
Han ChenHuman Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, United States.
Paul S de VriesHuman Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, United States.
James S FloydDepartment of Medicine, University of Washington, Seattle, WA, United States.
Nora FranceschiniDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, United States.
Xiuqing GuoThe Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, United States.
Jacklyn N HellwegeDivision of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
John S HouseBiostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Durham, NC, United States.
Chii-Min HwuSection of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Sharon L R KardiaDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, United States.
Ethan M LangeDivision of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Leslie A LangeDivision of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Caitrin W McDonoughDepartment of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, United States.
May E MontasserDivision of Endocrinology, Diabetes, and Nutrition, Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, United States.
Jeffrey R O'ConnellDepartment of Medicine, University of Maryland, Baltimore, MD, United States.
Megan M ShueyDivision of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
Xiao SunDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, United States.
Rikki M TannerDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, United States.
Zhe WangThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Wei ZhaoDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, United States.
April P CarsonDepartment of Medicine, University of Mississippi Medical Center, Jackson, MS, United States.
Todd L EdwardsVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, United States.
Tanika N KellyDivision of Nephrology, Department of Medicine, College of Medicine, University of Illinois Chicago, Chicago, IL, United States.
Eimear E KennyInstitute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Charles KooperbergDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, United States.
Ruth J F LoosThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Alanna C MorrisonHuman Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, United States.
Alison Motsinger-ReifBiostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Durham, NC, United States.
Bruce M PsatyCardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, United States.
Dabeeru C RaoDivision of Biostatistics, School of Medicine, Washington University in St. Louis, St. Louis, MO, United States.
Susan RedlineDivision of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States.
Stephen S RichDepartment of Public Health Sciences, Center for Public Health Genomics, University of Virginia, Charlottesville, VA, United States.
Jerome I RotterThe Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, United States.
Jennifer A SmithDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, United States.
Albert V SmithCenter for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, United States.
Marguerite R IrvinDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, United States.
Donna K ArnettOffice of the Provost, University of South Carolina, Columbia, SC, United States.
University of Michigan · USUniversity of Alabama at Birmingham · USThe University of Texas Health Science Center at Houston · USUCLA Medical Center · USUniversity of Maryland, Baltimore · USUniversity of Washington · USVanderbilt University Medical Center · USBrigham and Women's Hospital · USIcahn School of Medicine at Mount Sinai · USNational Institute of Environmental Health Sciences · USUniversity of Colorado Anschutz Medical Campus · USFred Hutch Cancer Center · USGenomic Health (United States) · USStanford University · USTaipei Veterans General Hospital · TWTulane University · USUniversity of Florida · USUniversity of Illinois Urbana-Champaign · USUniversity of Mississippi Medical Center · USUniversity of North Carolina at Chapel Hill · US

Funding

Large Scale Sequencing and Analysis of GenomesU54HG003067 · NHGRI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GABRIEL, STACEY, LANDER, ERIC S · 2004 to 2015
$568.6M
The Human Genome Sequencing CenterU54HG003273 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI GIBBS, RICHARD A · 2004 to 2015
$341.3M
IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVALR01HL092577 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI BENJAMIN, EMELIA J., ELLINOR, PATRICK THOMAS · 2009 to 2025
$20.6M
HYPERGEN: GENETICS OF LEFT VENTRICULAR HYPERTROPHYR01HL055673 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI ARNETT, DONNA K · 1996 to 2016
$18.1M
Studies of Rare Genetic Variation in the Isolated Population of SardiniaR01HL117626 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ABECASIS, GONCALO · 2013 to 2016
$10.5M
Building Interdisciplinary Research Careers in Women's HealthK12HD043483 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HARTMANN, KATHERINE E, MAJOR, AMY S · 2002 to 2023
$10.3M
CHARGE Consortium: Omics Discovery for CVD and Aging PhenotypesR01HL105756 · NHLBI · UNIVERSITY OF WASHINGTON · PI Bruce M Psaty, NICHOLAS L SMITH · 2011 to 2026
$9.5M
Rare variants and NHLBI traits in deeply phenotyped cohortsR01HL120393 · NHLBI · UNIVERSITY OF WASHINGTON · PI PSATY, BRUCE M, RICE, KENNETH M. · 2014 to 2016
$8.9M
MECHANISMS OF HYPERTENSION AND CARDIOVASCULAR DISEASEST32HL007457 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Martin E Young · 1985 to 2026
$8.6M
ASSOCIATION OF SLEEP DISORDERS WITH CARDIOVASCULAR HEALTH ACROSS ETHNIC GROUPSR01HL098433 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI REDLINE, SUSAN S. · 2010 to 2015
$8.2M
Phenotypic and Molecular Signatures for Sleep Apnea and Related MorbiditiesR35HL135818 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI REDLINE, SUSAN S. · 2017 to 2023
$7.2M
Rare Variants for Hypertension in Taiwan ChineseR01HL111249 · NHLBI · WASHINGTON UNIVERSITY · PI RAO, DABEERU C · 2012 to 2015
$6.4M
NHGRI NIH HHS U54 HG003067NHGRI NIH HHS U54 HG003273NHLBI NIH HHS HHSN268201100037CNHLBI NIH HHS HHSN268201500014CNHLBI NIH HHS HHSN268201500015CNHLBI NIH HHS HHSN268201800001CNHLBI NIH HHS K01 HL135405NHLBI NIH HHS R01 HL046380NHLBI NIH HHS R01 HL055673NHLBI NIH HHS R01 HL092577NHLBI NIH HHS R01 HL098433NHLBI NIH HHS R01 HL105756NHLBI NIH HHS R01 HL111249NHLBI NIH HHS R01 HL113338NHLBI NIH HHS R01 HL117626NHLBI NIH HHS R01 HL120393NHLBI NIH HHS R01 HL121007NHLBI NIH HHS R01 HL153805NHLBI NIH HHS R35 HL135818NHLBI NIH HHS T32 HL007457NHLBI NIH HHS U01 HL120393NICHD NIH HHS K12 HD043483NIDDK NIH HHS F31 DK108444NIDDK NIH HHS R01 DK117445NIEHS NIH HHS HHSN268201600032CNIEHS NIH HHS HHSN268201600033CNIMHD NIH HHS R01 MD012765
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antihypertensive responseblood pressureTOPMedtreatment resistant hypertensionwhole genome sequencing

Identifiers

PMID38162683
PMCPMC10755672
OpenAlexW4389678770

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.