Evidence map›Paper›PMID 38162608›Full record

ArticleFrontiers in public health2023

Health economics aspects of kidney transplantation in Sicily: a benchmark analysis on activity and estimated savings.

Roberto Cacciola, Francesca Leonardis, Lara Gitto, Evaldo Favi, Salvatore Gruttadauria, Marc Clancy, Massimiliano Veroux, Roberta Angelico, Duilio Pagano, Carmelo Mazzeo and 5 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Roberto Cacciola *Department of Surgical Sciences, Tor Vergata University, Rome, Italy.
Francesca Leonardis *Department of Surgical Sciences, Tor Vergata University, Rome, Italy.
Lara GittoDipartimento di Economia, Università Degli Studi di Messina, Messina, Italy.
Evaldo FaviGeneral Surgery and Kidney Transplantation, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Salvatore GruttadauriaDepartment for the Treatment and Study of Abdominal Diseases and Abdominal Transplantation, University of Istituto di Ricovero e Cura a Carattere Scientifico - Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, University of Pittsburgh Medical Center Italy, Palermo, Italy.
Marc ClancyInstitute of Cardiovascular and Molecular Sciences, Glasgow University, Glasgow, United Kingdom.
Massimiliano VerouxGeneral Surgery Unit, Organ Transplant Unit, University Hospital of Catania, Catania, Italy.
Roberta AngelicoDepartment of Surgical Sciences, Tor Vergata University, Rome, Italy.
Duilio PaganoDepartment for the Treatment and Study of Abdominal Diseases and Abdominal Transplantation, University of Istituto di Ricovero e Cura a Carattere Scientifico - Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, University of Pittsburgh Medical Center Italy, Palermo, Italy.
Carmelo MazzeoDepartment of Human Pathology, Emergency Surgery Unit, Università Degli Studi di Messina, Messina, Italy.
Irene CacciolaDepartment of Clinical and Experimental Medicine, Medicine and Hepatology Unit, Università Degli Studi di Messina, Messina, Italy.
Domenico SantoroDepartment of Clinical and Experimental Medicine, Nephrology and Dialysis Unit, Università Degli Studi di Messina, Messina, Italy.
Luca TotiDepartment of Surgical Sciences, Tor Vergata University, Rome, Italy.
Giuseppe TisoneDepartment of Surgical Sciences, Tor Vergata University, Rome, Italy.
Eugenio CucinottaGeneral Surgery Unit, Organ Transplant Unit, University Hospital of Catania, Catania, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: International and national registries consistently report substantial differences in kidney transplant (KT) activity despite demonstrable clinical and financial benefits. The study aims to estimate the financial resources gained by KT and produce a benchmark analysis that would inform adequate strategies for the growth of the service. Methods: We analyzed the KT activity in our region between 2017 and 2019. The benchmark analysis was conducted with programs identified from national and international registries. The estimate of financial resources was obtained by applying the kidney transplant coefficient of value; subsequently, we compared the different activity levels and savings generated by the three KT programs. Findings: The KT activity in the region progressively declined in the study years, producing a parallel reduction of the estimated savings. Such savings were substantially inferior when compared to those generated by benchmark programs (range €18-22 million less). Interpretation: The factors influencing the reduced KT activity in the study period with the related "foregone savings" are multiple, as well as interdependent. Organ donation, access to the transplant waiting list, and KT from living donors appear to be the most prominent determinants of the observed different levels of activities. International experience suggests that a comprehensive strategy in the form of a "task force" may successfully address the critical areas of the service reversing the observed trend. The financial impact of a progressively reduced KT activity may be as critical as its clinical implications, jeopardizing the actual sustainability of services for patients with end-stage kidney disease.

Indexed as

Kidney Failure, ChronicKidney TransplantationBenchmarkingHumansSicilyWaiting Listsaccess to transplantationbenchmarkingclinical governancehealth economicskidney transplantationkidney transplant waiting listliving donationorgan donation

Identifiers

PMID38162608
PMCPMC10757609

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.