Evidence map›Paper›PMID 38162577›Full record

ArticleFrontiers in cellular and infection microbiology2023

Pyrimidine salvage in

Hamza A A Elati, Amber L Goerner, Bruno Martorelli Di Genova, Lilach Sheiner, Harry P de Koning

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Role ofMicrobiology spectrum · 2026
    Article
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  8. Functional Studies of Kinetoplastid Transporters.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  9. TargetingFrontiers in microbiology · 2026
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Hamza A A ElatiSchool of Infection and Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Amber L GoernerLarner College of Medicine at The University of Vermont, Department of Microbiology and Molecular Genetics, Burlington, VT, United States.
Bruno Martorelli Di GenovaLarner College of Medicine at The University of Vermont, Department of Microbiology and Molecular Genetics, Burlington, VT, United States.
Lilach SheinerSchool of Infection and Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Harry P de KoningSchool of Infection and Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
University of Vermont · USUniversity Elmergib · LYUniversity of Glasgow · GBWellcome Centre for Molecular Parasitology · GB

Funding

Using Dengue Controlled Human Infection Model to Identify Adaptive Immune Correlates of ProtectionP20GM125498 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI Kristen Pierce · 2018 to 2026
$24.9M
NIGMS NIH HHS P20 GM125498Wellcome TrustWellcome Trust 104111
6 · The paper itself

Abstract

Toxoplasmosis is a common protozoan infection that can have severe outcomes in the immunocompromised and during pregnancy, but treatment options are limited. Recently, nucleotide metabolism has received much attention as a target for new antiprotozoal agents and here we focus on pyrimidine salvage by

Indexed as

ToxoplasmaToxoplasmosisDeoxyuridineHumansKineticsMembrane Transport ProteinsSulfadiazineThymidineUracilUridineDeoxyuridineMembrane Transport ProteinsSulfadiazineThymidineUracilUridine5-fluorodeoxyuridine5-fluorouracilantimetabolitefluoropyrimidinespyrimidine salvageToxoplasma gondiuracil transporteruridine transport

Identifiers

PMID38162577
PMCPMC10755004
OpenAlexW4389786011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.