Evidence map›Paper›PMID 38161589›Full record

ArticleFrontiers in aging neuroscience2023

The DNA repair enzyme, aprataxin, plays a role in innate immune signaling.

Helena B Madsen, Louise I Pease, Rebekah-Louise Scanlan, Mansour Akbari, Lene J Rasmussen, Daryl P Shanley, Vilhelm A Bohr

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in aging neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Helena B Madsen *Center for Healthy Aging, Institute of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
Louise I Pease *CAMPUS for Ageing and Vitality, Newcastle University, Newcastle, United Kingdom.
Rebekah-Louise ScanlanCAMPUS for Ageing and Vitality, Newcastle University, Newcastle, United Kingdom.
Mansour AkbariCenter for Healthy Aging, Institute of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
Lene J RasmussenCenter for Healthy Aging, Institute of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
Daryl P ShanleyCAMPUS for Ageing and Vitality, Newcastle University, Newcastle, United Kingdom.
Vilhelm A BohrCenter for Healthy Aging, Institute of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
University of Copenhagen · DKNewcastle University · GBNewcastle Hospitals - Campus for Ageing and Vitality · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ataxia with oculomotor apraxia type 1 (AOA1) is a progressive neurodegenerative disorder characterized by a gradual loss of coordination of hand movements, speech, and eye movements. AOA1 is caused by an inactivation mutation in the

Indexed as

APTXataxiaDNA- and RNA-sensing pathwaysDNA repairinnate immunitymicroglianeurodegenerative diseases

Identifiers

PMID38161589
PMCPMC10754971
OpenAlexW4389786056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.