Evidence map›Paper›PMID 38161431›Full record

ArticleFrontiers in pediatrics2023

Are lung ultrasound features more severe in infants with bronchiolitis and coinfections?

Domenico Umberto De Rose, Chiara Maddaloni, Ludovica Martini, Sara Ronci, Flaminia Pugnaloni, Gabriella Marrocco, Alessandra Di Pede, Velia Chiara Di Maio, Cristina Russo, Maria Paola Ronchetti and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Domenico Umberto De RoseNeonatal Intensive Care Unit, "Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.
Chiara MaddaloniNeonatal Intensive Care Unit, "Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.
Ludovica MartiniNeonatal Intensive Care Unit, "Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.
Sara RonciNeonatal Intensive Care Unit, "Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.
Flaminia PugnaloniNeonatal Intensive Care Unit, "Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.
Gabriella MarroccoNeonatal Sub-Intensive Care Unit and Follow-up, "Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.
Alessandra Di PedeNeonatal Sub-Intensive Care Unit and Follow-up, "Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.
Velia Chiara Di MaioMicrobiology and Diagnostic Immunology Unit, "Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.
Cristina RussoMicrobiology and Diagnostic Immunology Unit, "Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.
Maria Paola RonchettiNeonatal Intensive Care Unit, "Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.
Carlo Federico PernoMicrobiology and Diagnostic Immunology Unit, "Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.
Annabella BragugliaNeonatal Sub-Intensive Care Unit and Follow-up, "Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.
Flaminia CalzolariNeonatal Intensive Care Unit, "Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.
Andrea DottaNeonatal Intensive Care Unit, "Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.
Bambino Gesù Children's Hospital · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The lung ultrasound (LUS) score can be a useful tool to predict the need for respiratory support and the length of hospital stay in infants with bronchiolitis. Objective: To compare lung ultrasound features in neonates and infants up to three months of age with bronchiolitis to determine whether LUS scores (range 0-36) differ in infants with coinfections or not. Methods: Neonates and infants younger than three months admitted to neonatal units from October 2022 to March 2023, who underwent lung ultrasound evaluation on admission, were included in this retrospective study. Results: We included 60 patients who underwent LUS evaluation at admission. Forty-two infants (70.0%) had a single viral infection. Eighteen infants (30.0%) had a coinfection: fifteen infants (25.0%) had more than one virus at PCR; one infant (1.7%) had both a viral coinfection and a viral-bacteria coinfection; two infants (3.3%) had viral-bacteria coinfection. Infants with a single viral infection and those with coinfections had similar LUS scores globally and in different lung zones. An LUS score higher than 8 was identified to significantly predict the need for any respiratory support ( Conclusion: In our small cohort of neonates and infants younger than three months hospitalized with bronchiolitis, we found no statistically significant differences in the LUS score on admission between patients with a single viral infection and those with multiple infections.

Indexed as

bronchiolitisinfluenzaLUSnewbornsrespiratory infectionsrhinovirusRSVviruses

Identifiers

PMID38161431
PMCPMC10757344
OpenAlexW4389785877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.