Evidence map›Paper›PMID 38161375›Full record

ReviewACS central science2023

Radiochemistry: A Hot Field with Opportunities for Cool Chemistry.

Gregory D Bowden, Peter J H Scott, Eszter Boros

Open access · diamondAbstract readReview
In one paragraph

Review in ACS central science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Current status of radionuclide therapy targeting PARP in cancer: challenges and prospects.European journal of nuclear medicine and molecular imaging · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. The [18F] F-PSMA Probe: Chemical Perspectives.Current medicinal chemistry · 2025
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Improving the In Vivo Stability of [Journal of medicinal chemistry · 2024
    Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Gregory D BowdenDepartment of Radiology, University of Michigan, 1301 Catherine, Ann Arbor, Michigan 48109, United States.ORCID https://orcid.org/0000-0003-2274-6738
Peter J H ScottDepartment of Radiology, University of Michigan, 1301 Catherine, Ann Arbor, Michigan 48109, United States.
Eszter BorosDepartment of Chemistry, University of Wisconsin, 1101 University Avenue, Madison, Wisconsin 53706, United States.ORCID https://orcid.org/0000-0002-4186-6586
Siemens (Germany) · DEUniversity of Michigan · USUniversity of Wisconsin–Madison · US

Funding

Synthesis of Novel PET Radiotracers for Imaging in Alzheimer’s Disease and Related DisordersR01EB021155 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SANFORD, MELANIE S., SCOTT, PETER JAMES HENRY · 2016 to 2024
$3.2M
Harnessing the Radiochelation Chemistry of Theranostic, Rare Earth IsotopesR01EB032349 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI Eszter Boros · 2022 to 2026
$1.9M
NIBIB NIH HHS R01 EB021155NIBIB NIH HHS R01 EB032349
6 · The paper itself

Abstract

Recent Food and Drug Administration (FDA) approval of diagnostic and therapeutic radiopharmaceuticals and concurrent miniaturization of particle accelerators leading to improved access has fueled interest in the development of chemical transformations suitable for short-lived radioactive isotopes on the tracer scale. This recent renaissance of radiochemistry is paired with new opportunities to study fundamental chemical behavior and reactivity of elements to improve their production, separation, and incorporation into bioactive molecules to generate new radiopharmaceuticals. This outlook outlines pertinent challenges in the field of radiochemistry and indicates areas of opportunity for chemical discovery and development, including those of clinically established (C-11, F-18) and experimental radionuclides in preclinical development across the periodic table.

Identifiers

PMID38161375
PMCPMC10755734
OpenAlexW4388656518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.