Evidence map›Paper›PMID 38161374›Full record

ArticleACS central science2023

A Multiplexing Activity-Based Protein-Profiling Platform for Dissection of a Native Bacterial Xyloglucan-Degrading System.

Nicholas G S McGregor, Casper de Boer, Quentin P O Foucart, Thomas Beenakker, Wendy A Offen, Jeroen D C Codée, Lianne I Willems, Herman S Overkleeft, Gideon J Davies

Open access · diamondAbstract read
In one paragraph

Article in ACS central science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Bespoke Activity-Based Probes Reveal that theJournal of the American Chemical Society · 2025
    Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Nicholas G S McGregorDepartment of Chemistry, The University of York, Heslington, York YO10 5DD, United Kingdom.
Casper de BoerLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300 RA, Leiden, The Netherlands.
Quentin P O FoucartDepartment of Chemistry, The University of York, Heslington, York YO10 5DD, United Kingdom.
Thomas BeenakkerLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300 RA, Leiden, The Netherlands.ORCID https://orcid.org/0000-0002-9033-3065
Wendy A OffenDepartment of Chemistry, The University of York, Heslington, York YO10 5DD, United Kingdom.
Jeroen D C CodéeLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300 RA, Leiden, The Netherlands.ORCID https://orcid.org/0000-0003-3531-2138
Lianne I WillemsYork Structural Biology Laboratory and York Biomedical Research Institute, Department of Chemistry, University of York, Heslington, York YO10 5DD, United Kingdom.
Herman S OverkleeftLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300 RA, Leiden, The Netherlands.ORCID https://orcid.org/0000-0001-6976-7005
Gideon J DaviesDepartment of Chemistry, The University of York, Heslington, York YO10 5DD, United Kingdom.ORCID https://orcid.org/0000-0002-7343-776X
University of York · GBLeiden University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria and yeasts grow on biomass polysaccharides by expressing and excreting a complex array of glycoside hydrolase (GH) enzymes. Identification and annotation of such GH pools, which are valuable commodities for sustainable energy and chemistries, by conventional means (genomics, proteomics) are complicated, as primary sequence or secondary structure alignment with known active enzymes is not always predictive for new ones. Here we report a "low-tech", easy-to-use, and sensitive multiplexing activity-based protein-profiling platform to characterize the xyloglucan-degrading GH system excreted by the soil saprophyte,

Identifiers

PMID38161374
PMCPMC10755729
OpenAlexW4388978424

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.