Evidence map›Paper›PMID 38161219›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

A Paramagnetic Metal-Organic Framework Enhances Mild Magnetic Hyperthermia Therapy by Downregulating Heat Shock Proteins and Promoting Ferroptosis via Aggravation of Two-Way Regulated Redox Dyshomeostasis.

Yi Wang, Zelong Chen, Jiahui Li, Yafei Wen, Jiaxuan Li, Yinghua Lv, Zhichao Pei, Yuxin Pei

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
8.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 77 citations in OpenAlex.

  1. A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Review
  3. Stimuli-Responsive Supramolecular Biomaterials for Cancer Theranostics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Iron-MOFs for Biomedical Applications.Advanced healthcare materials · 2025
    Review
  12. Article
  13. EngineeredInternational journal of nanomedicine · 2025
    Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yi WangCollege of Chemistry and Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, P. R. China.
Zelong ChenCollege of Chemistry and Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, P. R. China.
Jiahui LiCollege of Chemistry and Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, P. R. China.
Yafei WenCollege of Chemistry and Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, P. R. China.
Jiaxuan LiCollege of Chemistry and Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, P. R. China.
Yinghua LvCollege of Chemistry and Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, P. R. China.
Zhichao PeiCollege of Chemistry and Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, P. R. China.
Yuxin PeiCollege of Chemistry and Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, P. R. China.ORCID 0000-0002-6316-9626
Northwest A&F University · CN

Funding

National Natural Science Foundation of China 22171230Science and Technology of Social Development in Shaanxi Province 2023-YBSF-151
6 · The paper itself

Abstract

Mild magnetic hyperthermia therapy (MMHT) holds great potential in treating deep-seated tumors, but its efficacy is impaired by the upregulation of heat shock proteins (HSPs) during the treatment process. Herein, Lac-FcMOF, a lactose derivative (Lac-NH

Indexed as

FerroptosisHyperthermia, InducedMetal-Organic FrameworksNeoplasmsAnimalsHeat-Shock ProteinsMagnetic FieldsMiceOxidation-ReductionHeat-Shock ProteinsMetal-Organic Frameworksferroptosisheat shock proteinsmild magnetic hyperthermia therapyparamagnetic metal-organic frameworkredox dyshomeostasis

Identifiers

PMID38161219
PMCPMC10953551
OpenAlexW4390488860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.