Evidence map›Paper›PMID 38160447›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2024

Connections between reproductive health and cognitive aging among women enrolled in the HCHS/SOL and SOL-INCA.

Ariana M Stickel, Wassim Tarraf, Sayaka Kuwayama, Benson Wu, Erin E Sundermann, Linda C Gallo, Melissa Lamar, Martha Daviglus, Donglin Zeng, Bharat Thyagarajan and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. GnRH and Cognition.Endocrinology · 2025
    Review
  8. Article
  9. Connections between reproductive health and cognitive aging among women enrolled in the HCHS/SOL and SOL-INCA.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 1 country.

Ariana M StickelDepartment of Psychology, San Diego State University, San Diego, California, USA.
Wassim TarrafInstitute of Gerontology & Department of Healthcare Sciences, Wayne State University, Detroit, Michigan, USA.
Sayaka KuwayamaDepartment of Neurosciences, University of California, San Diego, La Jolla, California, USA.
Benson WuDepartment of Neurosciences, University of California, San Diego, La Jolla, California, USA.
Erin E SundermannDepartment of Psychiatry, University of California, San Diego, La Jolla, California, USA.
Linda C GalloDepartment of Psychology, San Diego State University, San Diego, California, USA.
Melissa LamarInstitute for Minority Health Research, University of Illinois at Chicago, College of Medicine, Chicago, Illinois, USA.
Martha DaviglusInstitute for Minority Health Research, University of Illinois at Chicago, College of Medicine, Chicago, Illinois, USA.
Donglin ZengDepartment of Biostatistics, University of North Carolina, Chapel Hill, North Carolina, USA.
Bharat ThyagarajanDepartment of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.
Carmen R IsasiDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, New York, USA.
Richard B LiptonDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, New York, USA.
Christina CorderoDepartment of Psychology, University of Miami, Miami, Florida, USA.
Krista M PerreiraDepartment of Social Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
Hector M GonzalezDepartment of Neurosciences, University of California, San Diego, La Jolla, California, USA.
Sarah J BanksDepartment of Neurosciences, University of California, San Diego, La Jolla, California, USA.
University of California, San Diego · USAlbert Einstein College of Medicine · USSan Diego State University · USRush University Medical Center · USUniversity of Illinois Chicago · USUniversity of Miami · USUniversity of Minnesota Medical Center · USUniversity of North Carolina at Chapel Hill · USUniversity of North Carolina System · USWayne State University · US

Funding

UCSD Shiley-Marcos Alzheimer's Disease Research Center P30P30AG062429 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DOUGLAS R GALASKO · 2019 to 2026
$34.9M
Study of Latinos-Investigation of Neurocognitive Aging-Alzheimer's diseaseR01AG075758 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Charles DeCarli, Hector M Gonzalez · 2022 to 2026
$21.7M
SDSU FUERTE: Recognition of Excellence in DEIA and Mentorship in support of Faculty SuccessU54CA267789 · NCI · SAN DIEGO STATE UNIVERSITY · PI Mark Brian Reed, Maria Luisa Zuniga de Nuncio · 2021 to 2026
$15.5M
MRI Measures of Cerebrovascular Injury and AD Atrophy in a Study of LatinosRF1AG054548 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DECARLI, CHARLES, GONZALEZ, HECTOR M · 2017 to 2017
$14.7M
Study of Latinos Investigation of Neurocognitive Aging 2R56AG048642 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DECARLI, CHARLES, GONZALEZ, HECTOR M · 2020 to 2021
$8.7M
Neurocognitive aging, MCI and Alzheimer's disease DNA methylation among diverse LatinosRF1AG061022 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FORNAGE, MYRIAM, GONZALEZ, HECTOR M · 2019 to 2019
$6.6M
Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA)R01AG048642 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GONZALEZ, HECTOR M · 2015 to 2019
$5.7M
Sex-specific cognitive expression and risk in preclinical Alzheimer's diseaseR01AG066088 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BANKS, SARAH · 2019 to 2023
$3.9M
Culturally relevant contributors to cognitive and MRI changes in older LatinosR01AG062711 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI LAMAR, MELISSA · 2020 to 2025
$3.6M
Sex Differences in the Clinical Expression of Alzheimer's Disease Neuropathology and Their Underlying Biological MechanismsR01AG074221 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SUNDERMANN, ERIN ELIZABETH · 2021 to 2025
$2.7M
Thalassemia Clinical Research Network, CanadaU01HL065233 · NHLBI · UNIVERSITY HEALTH NETWORK · PI OLIVIERI, NANCY F · 2000 to 2009
$2.6M
Early and life course socioeconomic adversity and dementia risk in Hispanics/LatinosRF1AG077639 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI DECARLI, CHARLES, GONZALEZ, HECTOR M · 2022 to 2023
$1.9M
NCI NIH HHS U54 CA267789NHLBI NIH HHS N01 HC065233NHLBI NIH HHS N01 HC065234NHLBI NIH HHS N01 HC065235NHLBI NIH HHS N01 HC065236NHLBI NIH HHS N01 HC065237NIA NIH HHS K08 AG075351NIA NIH HHS L30 AG074401NIA NIH HHS P30 AG062429NIA NIH HHS R01 AG048642NIA NIH HHS R01AG048642NIA NIH HHS R01 AG062711NIA NIH HHS R01 AG066088NIA NIH HHS R01 AG074221NIA NIH HHS R01 AG075758NIA NIH HHS R56 AG048642NIA NIH HHS R56AG048642NIA NIH HHS RF1 AG054548NIA NIH HHS RF1AG054548NIA NIH HHS RF1 AG061022NIA NIH HHS RF1AG061022NIA NIH HHS RF1 AG077639NINDS NIH HHS R25 NS117367
6 · The paper itself

Abstract

introductionReproductive health history may contribute to cognitive aging and risk for Alzheimer's disease, but this is understudied among Hispanic/Latina women.

methodsParticipants included 2126 Hispanic/Latina postmenopausal women (44 to 75 years) from the Study of Latinos-Investigation of Neurocognitive Aging. Survey linear regressions separately modeled the associations between reproductive health measures (age at menarche, history of oral contraceptive use, number of pregnancies, number of live births, age at menopause, female hormone use at Visit 1, and reproductive span) with cognitive outcomes at Visit 2 (performance, 7-year change, and mild cognitive impairment [MCI] prevalence).

resultsYounger age at menarche, oral contraceptive use, lower pregnancies, lower live births, and older age at menopause were associated with better cognitive performance. Older age at menarche was protective against cognitive change. Hormone use was linked to lower MCI prevalence. DISCUSSION: Several aspects of reproductive health appear to impact cognitive aging among Hispanic/Latina women.

Indexed as

Cognitive AgingContraceptives, OralFemaleHormonesHumansMenopausePregnancyReproductive HealthContraceptives, OralHormonescognitionHispanicsLatinasmenopausemild cognitive impairmentreproductive healthwomen

Identifiers

PMID38160447
PMCPMC10947951
OpenAlexW4390459600

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.