Evidence map›Paper›PMID 38160441›Full record

ArticleArchives of gynecology and obstetrics2024

Development and validation of a nomogram for individualized prediction of spontaneous extremely preterm birth at < 28 weeks in twin pregnancy: a retrospective cohort study.

Min Lv, Cheng Chen, Huaqin Yang, Ying Lou, Juan Li, Baihui Zhao, Danqing Chen, Qiong Luo

Abstract readValidation Study
PubMed Publisher
In one paragraph

Article in Archives of gynecology and obstetrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Min Lv *Key Laboratory of Women's Reproductive Health of Zhejiang Province, School of Medicine, Women's Hospital, Zhejiang University, Hangzhou, China.
Cheng Chen *Key Laboratory of Women's Reproductive Health of Zhejiang Province, School of Medicine, Women's Hospital, Zhejiang University, Hangzhou, China.
Huaqin Yang *Key Laboratory of Women's Reproductive Health of Zhejiang Province, School of Medicine, Women's Hospital, Zhejiang University, Hangzhou, China.
Ying LouKey Laboratory of Women's Reproductive Health of Zhejiang Province, School of Medicine, Women's Hospital, Zhejiang University, Hangzhou, China.
Juan LiKey Laboratory of Women's Reproductive Health of Zhejiang Province, School of Medicine, Women's Hospital, Zhejiang University, Hangzhou, China.
Baihui ZhaoKey Laboratory of Women's Reproductive Health of Zhejiang Province, School of Medicine, Women's Hospital, Zhejiang University, Hangzhou, China.
Danqing ChenKey Laboratory of Women's Reproductive Health of Zhejiang Province, School of Medicine, Women's Hospital, Zhejiang University, Hangzhou, China. chendq@zju.edu.cn.
Qiong LuoKey Laboratory of Women's Reproductive Health of Zhejiang Province, School of Medicine, Women's Hospital, Zhejiang University, Hangzhou, China. luoq@zju.edu.cn.ORCID 0000-0002-0782-4462
Women's Hospital, School of Medicine, Zhejiang University · CNMinistry of Education · NZTaizhou Central Hospital · CN

Funding

National Nature Science Foundation of China 81571447Natural Science Foundation of Zhejiang Province LY20H040009Scientific Research Foundation of the National Health Commission WKJ-ZJ-2126
6 · The paper itself

Abstract

purposeTo develop a nomogram to predict spontaneous preterm birth at < 28 weeks in pregnant women with twin pregnancies.

methodsWe retrospectively studied the medical records of twin-pregnancy women with asymptomatic cervical dilation or cervical shortening between December 2015 to February 2022 in two hospitals. Data from one center was used to develop the model and data from the other was used to evaluate the model.

resultsA total of 270 twin pregnancies were enrolled in the study. We incorporated 4 items (cervical length, cervical dilation, C-reactive protein and the use of cerclage) to build the 28-week nomogram with satisfactory discrimination and calibration when applied to the validation sets. The C index for the 28-week nomogram in the development and external cohort was 0.88 (95% CI, 0.84-0.93) and 0.89 (95% CI, 0.80-0.98), respectively. The nomogram reached a sensitivity of 70.70%, specificity of 97.10%, positive predicted value of 95.61% and negative predicted value of 78.77%. Moreover, the decision curve analysis indicated that the nomogram showed positive clinical benefit.

conclusionWe developed and validated a nomogram with good performance in predicting individual risk of spontaneous preterm birth at < 28 in twin pregnancy.

Indexed as

Cervical Length MeasurementNomogramsPregnancy, TwinPremature BirthAdultCerclage, CervicalC-Reactive ProteinFemaleGestational AgeHumansPredictive Value of TestsPregnancyRetrospective StudiesRisk AssessmentC-Reactive ProteinCerclageCervical insufficiencyNomogramSpontaneous preterm birthTwin pregnancy

Identifiers

PMID38160441
OpenAlexW4390466002

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.