ArticleCell reports2024
Two-pore channel-2 and inositol trisphosphate receptors coordinate Ca
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Article in Cell reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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0cells of the map it votes in
24citing papers in PubMed
8.8field-weighted citation impact, top 2% of its field
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Who cites it
24 citing papers in PubMed, 34 citations in OpenAlex.
- Positive-Sense RNA Viruses Reprogramming Membrane Contact Sites to Remodel Organelles and Control Cell Fate.Viruses · 2026Review
- Allosteric switching of CaThe EMBO journal · 2026Article
- IP3R2-mediated inter-organelle calcium signaling suppresses melanosome degradation.PLoS biology · 2026Article
- Ryanodine Receptor 1 Is Dispensable for CD4European journal of immunology · 2026Article
- Two-pore channel-2 controls calmodulin-dependent STIM1 inactivation.Nature communications · 2026Article
- The lysosomal cation channel TRPML1 regulates the oligodendrocyte cytoskeleton.bioRxiv : the preprint server for biology · 2026Article
- O-linked glycan-dependent gating of TPC2 controls lysosomal excitability and organelle remodeling.Nature communications · 2026Article
- Review
- Inactive ryanodine receptors sustain lysosomal availability for autophagy by promoting ER-lysosomal contact site formation.Nature communications · 2026Article
- Liquid liquid phase separation of the intrinsically disordered protein JPT2 compartmentalizes components of NAADP-evoked CabioRxiv : the preprint server for biology · 2026Article
- Lysosomal dysfunction in diabetes and diabetic complications.Frontiers in endocrinology · 2026Review
- Palmitate impairs autophagic degradation via oxidative stress/perilysosomal Ca2+ overload/mTORC1 activation pathway in pancreatic β cells.JCI insight · 2025Article
- Review
- Key challenges and recommendations for defining organelle membrane contact sites.Nature reviews. Molecular cell biology · 2025Review
- Inter-Organellar CaCells · 2025Review
- Pancreatic acinar cell signalling and function exhibit an absolute requirement for activation of GαThe Journal of physiology · 2025Article
- The roles of mitochondria in global and local intracellular calcium signalling.Nature reviews. Molecular cell biology · 2025Review
- Agonist-Triggered Ca2+ Release From Functionally Connected Endoplasmic Reticulum and Lysosomal Ca2+ Stores in bEND.3 Endothelial Cells.Physiological research · 2025Article
- Lysosomal Ion Channels and Transporters: Recent Findings, Therapeutic Potential, and Technical Approaches.Bioelectricity · 2025Review
- The IPBiochimica et biophysica acta. Molecular basis of disease · 2025Article
Corrections and comments
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Authors and funding
14 authors at 7 institutions in 5 countries.
Yu YuanDepartment of Cell and Developmental Biology, University College London, Gower Street, WC1E 6BT London, UK.
Vikas ArigeDepartment of Pharmacology and Physiology, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA.
Ryo SaitoDepartment of Cell and Developmental Biology, University College London, Gower Street, WC1E 6BT London, UK; Department of Dermatology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Qianru MuDepartment of Cell and Developmental Biology, University College London, Gower Street, WC1E 6BT London, UK.
Gabriela C BrailoiuDepartment of Pharmaceutical Sciences, Jefferson College of Pharmacy, Thomas Jefferson University, 901 Walnut Street, Philadelphia, PA 19107, USA.
Gustavo J S PereiraDepartment of Cell and Developmental Biology, University College London, Gower Street, WC1E 6BT London, UK; Department of Pharmacology, Federal University of São Paulo (UNIFESP), São Paulo 04044-020, Brazil.
Stephen R BolsoverDepartment of Cell and Developmental Biology, University College London, Gower Street, WC1E 6BT London, UK.
Marco KellerDepartment of Pharmacy-Center for Drug Research, Ludwig-Maximilian University, Butenandtstrasse 5-13, 81377 Munich, Germany.
Franz BracherDepartment of Pharmacy-Center for Drug Research, Ludwig-Maximilian University, Butenandtstrasse 5-13, 81377 Munich, Germany.
Christian GrimmWalther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilian University, Nussbaumstrasse 26, 80336 Munich, Germany; Immunology, Infection and Pandemic Research IIP, Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, 60596 Frankfurt, Germany.
Eugen BrailoiuDepartment of Neural Sciences and Center for Substance Abuse Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Jonathan S MarchantDepartment of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.
David I YuleDepartment of Pharmacology and Physiology, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA. Electronic address: david_yule@urmc.rochester.edu.
Sandip PatelDepartment of Cell and Developmental Biology, University College London, Gower Street, WC1E 6BT London, UK. Electronic address: patel.s@ucl.ac.uk.
University College London · GBLudwig-Maximilians-Universität München · DEUniversity of Rochester · USFraunhofer Institute for Translational Medicine and Pharmacology · DEMedical College of Wisconsin · USTemple University · USThomas Jefferson University · US
Funding
Functional architecture of IP3-evoked local Ca2+ signalsR01GM088790 · NIGMS · UNIVERSITY OF MINNESOTA · PI MARCHANT, JONATHAN S, SLAMA, JAMES T · 2009 to 2025
$4.7MSARS-CoV-2 signaling and interactions with stimulant drugs of abuse via Sigma-1R: Impact on the BBBR01DA054921 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI Gabriela Cristina Brailoiu, ELLEN M UNTERWALD · 2022 to 2026
$2.4MDeciphering the complex pharmacology of CB1: towards the understanding of a third signaling pathwayR21DA056729 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI BRAILOIU, EUGEN, WARD, SARA J · 2023 to 2024
$436kNIDA NIH HHS R01 DA054921NIDA NIH HHS R21 DA056729NIGMS NIH HHS R01 GM088790
Abstract
Lysosomes and the endoplasmic reticulum (ER) are Ca
Indexed as
Calcium SignalingTwo-Pore ChannelsCalciumEndoplasmic ReticulumInositolInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate ReceptorsLysosomesNADPCalciumInositolInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate ReceptorsNADPTwo-Pore ChannelsCa(2+) storesCP: Cell biologyendoplasmic reticulumhistamineIP(3)IP(3) receptorslysosomesNAADPpuffstuffstwo-pore channels
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.