Evidence map›Paper›PMID 38159942›Full record

ArticleBMJ open2023

Peer support impact on therapeutic adherence in patients with multiple sclerosis: a mixed-methods pilot trial protocol.

Léonor Guilmault, Sandrine Wiertlewski, Lucie Malloggi, Cécilia Rousseau, Marylène Jacq-Foucher, Brice Leclere, Leila Moret

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05519553 (Peer Support Impact on Therapeutic Adherence in Patients With Multiple Sclerosis), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05519553 naactive not recruitingnot on this map

Peer Support Impact on Therapeutic Adherence in Patients With Multiple Sclerosis: a Mixed Methods Randomized Controlled Trial Pilot Study

TypeinterventionalSponsorNantes University HospitalRan2023 to 2026Enrolled60ConditionsMultiple Sclerosis, Relapsing-remittingArmsPeer support
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Léonor GuilmaultService de santé publique, Nantes University Hospital, Nantes, France.ORCID 0000-0002-4334-7157
Sandrine WiertlewskiService de neurologie, Nantes University Hospital, Nantes, France.
Lucie MalloggiService de santé publique, Nantes University Hospital, Nantes, France.
Cécilia RousseauService de santé publique, Nantes University Hospital, Nantes, France.
Marylène Jacq-FoucherService de neurologie, Nantes University Hospital, Nantes, France.
Brice LeclereService de santé publique, Nantes University Hospital, Nantes, France.
Leila MoretService de santé publique, Nantes University Hospital, Nantes, France leila.moret@chu-nantes.fr.
Centre Hospitalier Universitaire de Nantes · FRHôpital Saint-Jacques · FRUniversité de Tours · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatient partnership is a key component of patient-centred care. One form of partnership is individual peer support, which can improve patients' quality of life and adherence to treatment. Patient with multiple sclerosis could benefit from this type of support, but such an intervention has not been explored in the literature.We propose in this article a pilot study protocol to assess the feasibility and acceptability of healthcare-integrated individual peer support, and the feasibility of a large-scale efficacy trial. METHODS AND ANALYSIS: The PAIR-SEP study is a mixed-methods pilot clinical trial combining quantitative and qualitative approaches. Sixty patients with relapsing-remitting multiple sclerosis undergoing drug therapy from the Neurology centre of Nantes University Hospital (France) will be randomised on a 1:1 ratio to receive either usual care only or usual care combined with peer support (three individual sessions at 1, 3 and 5 months with a peer helper).We will evaluate clinical outcomes in preparation of the large-scale trial: therapeutic adherence 6 months after baseline, therapeutic compliance, quality of life, anxiety and depression, social support. All dimensions will be assessed using validated health questionnaires at baseline and at 6 months.Intervention's acceptability and feasibility will be evaluated using qualitative methods: undirected interviews with patients from the intervention group and separate focus-groups with the peer helpers the healthcare team. ETHICS AND DISSEMINATION: Ethical approval was obtained from the local ethics committee on 1 October 2022. This study was designed in collaboration with multiple sclerosis peer helpers.The trial findings will be published in peer-reviewed journals. TRIAL REGISTRATION NUMBER: NCT05519553.

Indexed as

Multiple SclerosisCounselingFeasibility StudiesHumansPilot ProjectsQuality of LifeSocial SupportMedication AdherenceMultiple sclerosisPatient-Centered CarePatient ParticipationQuality of Life

Identifiers

PMID38159942
PMCPMC10759089
OpenAlexW4390452009

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.