Evidence map›Paper›PMID 38159252›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2024

Lifetime occupational skill and later-life cognitive function among older adults in the United States, Mexico, India, and South Africa.

Lindsay C Kobayashi, Brendan Q O'Shea, Caroline Wixom, Richard N Jones, Kenneth M Langa, David Weir, Jinkook Lee, Rebeca Wong, Alden L Gross

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Lifespan exposures to rural-urban conditions and later-life cognitive function.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  7. Shorter Telomere Length in Individuals with Neurocognitive Disorder andInternational journal of molecular sciences · 2025
    Article
  8. Physical and mental demands of work associated with dementia risk in later life.The journal of prevention of Alzheimer's disease · 2025
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lindsay C KobayashiCenter for Social Epidemiology and Population Health, Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, USA.ORCID 0000-0003-2725-3107
Brendan Q O'SheaCenter for Social Epidemiology and Population Health, Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, USA.
Caroline WixomSurvey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, USA.
Richard N JonesDepartment of Psychiatry and Human Behavior, Alpert Medical School, Brown University, Providence, USA.
Kenneth M LangaSurvey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, USA.
David WeirSurvey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, USA.
Jinkook LeeCenter for Economic and Social Research, University of Southern California, Los Angeles, California, USA.
Rebeca WongSealy Center on Aging, University of Texas Medical Branch, Galveston, Texas, USA.
Alden L GrossDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Integrting Information About Aging SurveysR01AG030153 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Sara Adar, Alden L. Gross · 2007 to 2026
$41.7M
Leveraging a natural experiment to estimate the causal impact of blood sugar on dementia and cognition in IndiaR01AG051125 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jinkook Lee · 2015 to 2026
$26.8M
The Mexican Health and Aging Study - IIR01AG018016 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Rebeca Wong · 1999 to 2026
$22.6M
The Longitudinal Aging Study in IndiaR01AG042778 · NIA · HARVARD SCHOOL OF PUBLIC HEALTH · PI AROKIASAMY, PERIANAYAGAM, BLOOM, DAVID E · 2013 to 2019
$9.0M
Health and Retirement Study: Harmonized Cognitive Assessment Protocol (HCAP)U01AG058499 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LANGA, KENNETH M · 2018 to 2023
$8.3M
Socioeconomic, Cardiovascular, and Psychosocial Sources of Cross-National Variation in Cognitive Health Among Older AdultsR01AG070953 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Alden L. Gross, Lindsay C Kobayashi · 2021 to 2026
$4.6M
Research Network for the Harmonized Cognitive Assessment Protocol (HCAP): Years 6-10U24AG065182 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lindsay C Kobayashi, KENNETH M LANGA · 2022 to 2026
$2.6M
MHAS Cognitive Aging Ancillary Study Administrative SupplementR01AG051158 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI WONG, REBECA · 2015 to 2017
$1.1M
NIA NIH HHS R01 AG018016NIA NIH HHS R01 AG030153NIA NIH HHS R01 AG042778NIA NIH HHS R01 AG051125NIA NIH HHS R01 AG051158NIA NIH HHS R01 AG070953NIA NIH HHS U01 AG009740NIA NIH HHS U01 AG058499NIA NIH HHS U24 AG065182
6 · The paper itself

Abstract

introductionWe conducted a cross-national comparison of the association between main lifetime occupational skills and later-life cognitive function across four economically and socially distinct countries.

methodsData were from population-based studies of aging and their Harmonized Cognitive Assessment Protocols (HCAPs) in the US, South Africa, India, and Mexico (N = 10,037; Age range: 50 to 105 years; 2016 to 2020). Main lifetime occupational skill was classified according to the International Standard Classification of Occupations. Weighted, adjusted regression models estimated pooled and country-specific associations between main lifetime occupational skill and later-life general cognitive function in men and women.

resultsWe observed positive gradients between occupational skill and later-life cognitive function for men and women in the US and Mexico, a positive gradient for women but not men in India, and no association for men or women in South Africa. DISCUSSION: Main lifetime occupations may be a source of later-life cognitive reserve, with cross-national heterogeneity in this association. HIGHLIGHTS: No studies have examined cross-national differences in the association of occupational skill with cognition. We used data from Harmonized Cognitive Assessment Protocols in the US, Mexico, India, and South Africa. The association of occupational skill with cognitive function varies by country and gender.

Indexed as

AgingCognitionAgedAged, 80 and overFemaleHumansMaleMexicoMiddle AgedOccupationsSouth AfricaUnited Statesagingcognitive functioncross-national comparisongenderoccupationrisk factorswork environment

Identifiers

PMID38159252
PMCPMC10947921

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.