Evidence map›Paper›PMID 38159167›Full record

ReviewCurrent hypertension reports2024

Update on the Use of Pulse Wave Velocity to Measure Age-Related Vascular Changes.

Andrea G Marshall, Kit Neikirk, Jeremiah Afolabi, Naome Mwesigwa, Bryanna Shao, Annet Kirabo, Anilkumar K Reddy, Antentor Hinton

Open access · greenAbstract readReview
In one paragraph

Review in Current hypertension reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 39 citations in OpenAlex.

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  16. How to measure and model cardiovascular aging.Cardiovascular research · 2025
    Review
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  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Andrea G Marshall *Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.
Kit Neikirk *Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.
Jeremiah AfolabiDepartment of Medicine, Vanderbilt University Medical Center, 750 Robinson Research Building, 2200 Pierce Ave, Nashville, TN, 37232-0615, USA.
Naome MwesigwaDepartment of Medicine, Vanderbilt University Medical Center, 750 Robinson Research Building, 2200 Pierce Ave, Nashville, TN, 37232-0615, USA.
Bryanna ShaoDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.
Annet KiraboDepartment of Medicine, Vanderbilt University Medical Center, 750 Robinson Research Building, 2200 Pierce Ave, Nashville, TN, 37232-0615, USA.
Anilkumar K Reddy *Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA.
Antentor HintonDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA. Antentor.o.hinton.jr@vanderbilt.edu.
Vanderbilt University · USVanderbilt University Medical Center · USBaylor College of Medicine · US

Funding

Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI OWEN P MCGUINNESS · 2012 to 2026
$29.3M
PRIDE: Functional and Translational Genomics of Blood DisordersR25HL106365 · NHLBI · AUGUSTA UNIVERSITY · PI PACE, BETTY SUE · 2010 to 2024
$5.2M
ENaC regulation and its role in blood pressure homeostasisR01HL147818 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Annet Kirabo, Thomas R Kleyman · 2019 to 2026
$4.6M
Immune Mechanisms of Salt-Sensitive hypertensionR01HL144941 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KIRABO, ANNET · 2021 to 2025
$3.0M
Salt taste sensitivity, genetics and salt sensitivity of blood pressure in HIVR21TW012635 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KIRABO, ANNET, MASENGA, SEPISO KENIAS · 2023 to 2024
$385k
Deep phenotypic and functional characterization of salt-responsive immune cells in human salt senstive hypertension using CTE-seqR03HL155041 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KIRABO, ANNET · 2021 to 2022
$173k
FIC NIH HHS R21 TW012635NHLBI NIH HHS R01 HL144941NHLBI NIH HHS R01 HL147818NHLBI NIH HHS R03 HL155041NHLBI NIH HHS R25 HL106365NIDDK NIH HHS P30 DK020593NIDDK NIH HHS R03HL155041, R01HL147818, R01HL144941 and R21TW012635NIH HHS 5R25HL106365-12
6 · The paper itself

Abstract

purpose of reviewPulse wave velocity (PWV) is an important and well-established measure of arterial stiffness that is strongly associated with aging. Age-related alterations in the elastic properties and integrity of arterial walls can lead to cardiovascular disease. PWV measurements play an important role in the early detection of these changes, as well as other cardiovascular disease risk factors, such as hypertension. This review provides a comprehensive summary of the current knowledge of the effects of aging on arterial stiffness, as measured by PWV. RECENT

findingsThis review highlights recent findings showing the applicability of PWV analysis for investigating heart failure, hypertension, and other cardiovascular diseases, as well as cerebrovascular diseases and Alzheimer's disease. It also discusses the clinical implications of utilizing PWV to monitor treatment outcomes, various challenges in implementing PWV assessment in clinical practice, and the development of new technologies, including machine learning and artificial intelligence, which may improve the usefulness of PWV measurements in the future. Measuring arterial stiffness through PWV remains an important technique to study aging, especially as the technology continues to evolve. There is a clear need to leverage PWV to identify interventions that mitigate age-related increases in PWV, potentially improving CVD outcomes and promoting healthy vascular aging.

Indexed as

Cardiovascular DiseasesHypertensionVascular StiffnessArteriesArtificial IntelligenceHumansPulse Wave AnalysisArterial stiffnessCardiovascular diseasePhysiologyPulse wave velocityTherapiesVascular

Identifiers

PMID38159167
PMCPMC10955453
OpenAlexW4390442349

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.