Evidence map›Paper›PMID 38159130›Full record

ArticlePflugers Archiv : European journal of physiology2024

The role of HCN channels on the effects of T-type calcium channels and GABA

Emre Soner Tiryaki, Gökhan Arslan, Caner Günaydın, Mustafa Ayyıldız, Erdal Ağar

Abstract read
PubMed Publisher
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Emre Soner TiryakiDepartment of Physiology, Faculty of Medicine, University of Ondokuz Mayıs, Samsun, Türkiye.
Gökhan ArslanDepartment of Physiology, Faculty of Medicine, University of Ondokuz Mayıs, Samsun, Türkiye. gokhan.arslan@omu.edu.tr.
Caner GünaydınDepartment of Pharmacology, Faculty of Medicine, University of Samsun, Samsun, Türkiye.
Mustafa AyyıldızDepartment of Physiology, Faculty of Medicine, University of Ondokuz Mayıs, Samsun, Türkiye.
Erdal AğarDepartment of Physiology, Faculty of Medicine, University of Ondokuz Mayıs, Samsun, Türkiye.
Ondokuz Mayıs University · TRSamsun University · TR

Funding

Scientific Research Projects of Ondokuz Mayıs University PYO.TIP.1904.20.009
6 · The paper itself

Abstract

In this study we used ivabradine (IVA), a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker, to identify its effect on spike-wave discharges (SWDs); and aimed to determine the role of IVA on the effects of T-type calcium channel blocker NNC 55-0396, GABA

Indexed as

Calcium Channels, T-TypeEpilepsy, AbsenceAnimalsAnticonvulsantsBicucullineCalcium Channel BlockersDisease Models, AnimalElectroencephalographygamma-Aminobutyric AcidHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsMaleMuscimolRatsRats, WistarReceptors, GABA-AAnticonvulsantsBicucullineCalcium Channel BlockersCalcium Channels, T-Typegamma-Aminobutyric AcidHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsMuscimolReceptors, GABA-AAbsence epilepsyGABAA receptorHCN channelsIvabradineSpike-wave dischargesT-type calcium channelsWAG/Rij rat

Identifiers

PMID38159130
OpenAlexW4390444531

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.