Evidence map›Paper›PMID 38158807›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2023

Transcriptomic profile of the mechanosensitive ion channelome in human cardiac fibroblasts.

Vadim Mitrokhin, Andrei Bilichenko, Viktor Kazanski, Roman Schobik, Stanislav Shileiko, Veronika Revkova, Vladimir Kalsin, Olga Kamkina, Andre Kamkin, Mitko Mladenov

Open access · greenAbstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. CaBiomedicines · 2025
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Vadim MitrokhinDepartment of Physiology, Pirogov Russian National Research Medical University, Moscow 117997, Russia.
Andrei BilichenkoDepartment of Physiology, Pirogov Russian National Research Medical University, Moscow 117997, Russia.
Viktor KazanskiDepartment of Physiology, Pirogov Russian National Research Medical University, Moscow 117997, Russia.
Roman SchobikDepartment of Physiology, Pirogov Russian National Research Medical University, Moscow 117997, Russia.
Stanislav ShileikoDepartment of Physiology, Pirogov Russian National Research Medical University, Moscow 117997, Russia.
Veronika RevkovaDepartment of Physiology, Pirogov Russian National Research Medical University, Moscow 117997, Russia.
Vladimir KalsinDepartment of Physiology, Pirogov Russian National Research Medical University, Moscow 117997, Russia.
Olga KamkinaDepartment of Physiology, Pirogov Russian National Research Medical University, Moscow 117997, Russia.
Andre KamkinDepartment of Physiology, Pirogov Russian National Research Medical University, Moscow 117997, Russia.
Mitko MladenovDepartment of Physiology, Pirogov Russian National Research Medical University, Moscow 117997, Russia.ORCID 0000-0003-3475-2131
Pirogov Russian National Research Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human cardiac fibroblasts (HCFs) have mRNA transcripts that encode different mechanosensitive ion channels and channel regulatory proteins whose functions are not known yet. The primary goal of this work was to define the mechanosensitive ion channelome of HCFs. The most common type of cationic channel is the transient receptor potential (TRP) family, which is followed by the TWIK-related K

Indexed as

Transient Receptor Potential ChannelsTRPM Cation ChannelsFibroblastsGene Expression ProfilingHeartHumansProtein Serine-Threonine KinasesRNA, MessengerTranscriptomeMCOLN3 protein, humanProtein Serine-Threonine KinasesRNA, MessengerTransient Receptor Potential ChannelsTRPM7 protein, humanTRPM Cation ChannelschannelomeHuman cardiac fibroblastsmechanosensitive cation channelsmRNAstretch-activated channelstranscriptomic profile

Identifiers

PMID38158807
PMCPMC10903254
OpenAlexW4390448479

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.