Evidence map›Paper›PMID 38157998›Full record

ArticlePharmacological research2024

β-arrestin biased signaling is not involved in the hypotensive actions of 5-HT

Stephanie W Watts, Hannah Garver, Severine Morisset-Lopez, Franck Suzenet, Gregory D Fink

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmacological research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Stephanie W WattsDepartment of Pharmacology and Toxicology, Michigan State University, East Lansing, MI 48824-1317, USA. Electronic address: wattss@msu.edu.
Hannah GarverDepartment of Pharmacology and Toxicology, Michigan State University, East Lansing, MI 48824-1317, USA.
Severine Morisset-LopezCentre de Biophysique Moléculaire, CNRS, Unité Propre de Recherche 4301, Université d'Orléans, Orléans Cedex 2 45071 France.
Franck SuzenetInstitut de Chimie Organique et Analytique, Université d'Orléans, CNRS UMR 7311, rue de Chartres, 45067 Orléans, France.
Gregory D FinkDepartment of Pharmacology and Toxicology, Michigan State University, East Lansing, MI 48824-1317, USA.
Michigan State University · USCentre de Biophysique Moléculaire · FRInstitut de Chimie Organique et Analytique · FR

Funding

5-HT7 receptor and blood pressure regulationR01HL151413 · NHLBI · MICHIGAN STATE UNIVERSITY · PI FINK, GREGORY D, WATTS, STEPHANIE W · 2020 to 2023
$1.7M
NHLBI NIH HHS R01 HL151413
6 · The paper itself

Abstract

The 5-hydroxytryptamine 7 receptor (5-HT

Indexed as

HypotensionSerotoninAnimalsbeta-ArrestinsMaleRatsRats, Sprague-DawleySerotonin Receptor Agonistsbeta-ArrestinsSerotoninSerotonin Receptor Agonists5-HT5-HT(7) receptorBiased agonistCardiovascular diseaseHypotension

Identifiers

PMID38157998
PMCPMC11416702
OpenAlexW4390349658

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.