Evidence map›Paper›PMID 38157878›Full record

ReviewArquivos de neuro-psiquiatria2023

Reshaping neuroimmunology: diagnosis and treatment in the era of precision medicine.

Giordani Rodrigues Dos Passos, Tarso Adoni, Maria Fernanda Mendes, Douglas Kazutoshi Sato

Open access · goldAbstract readReview
In one paragraph

Review in Arquivos de neuro-psiquiatria, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. A journey through 80 years of Brazilian neurology.Arquivos de neuro-psiquiatria · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Giordani Rodrigues Dos PassosPontifícia Universidade Católica do Rio Grande do Sul, Escola de Medicina e Instituto do Cérebro do Rio Grande do Sul, Porto Alegre RS, Brazil.ORCID 0000-0002-8949-6115
Tarso AdoniUniversidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, São Paulo SP, Brazil.ORCID 0000-0002-5008-2783
Maria Fernanda MendesSanta Casa de São Paulo, Faculdade de Ciências Médicas, São Paulo SP, Brazil.ORCID 0000-0003-3983-6019
Douglas Kazutoshi SatoPontifícia Universidade Católica do Rio Grande do Sul, Escola de Medicina e Instituto do Cérebro do Rio Grande do Sul, Porto Alegre RS, Brazil.ORCID 0000-0002-7695-6020
Instituto do Cérebro · BRFaculdade de Ciências Médicas da Santa Casa de São Paulo · BRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precision medicine has revolutionized the field of neuroimmunology, with innovative approaches that characterize diseases based on their biology, deeper understanding of the factors leading to heterogeneity within the same disease, development of targeted therapies, and strategies to tailor therapies to each patient. This review explores the impact of precision medicine on various neuroimmunological conditions, including multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), optic neuritis, autoimmune encephalitis, and immune-mediated neuropathies. We discuss advances in disease subtyping, recognition of novel entities, promising biomarkers, and the development of more selective monoclonal antibodies and cutting-edge synthetic cell-based immunotherapies in neuroimmunological disorders. In addition, we analyze the challenges related to affordability and equity in the implementation of these emerging technologies, especially in situations with limited resources.

Indexed as

EncephalitisHashimoto DiseaseNeuromyelitis OpticaOptic NeuritisAntibodies, MonoclonalAquaporin 4AutoantibodiesHumansImmunotherapyMyelin-Oligodendrocyte GlycoproteinPrecision MedicineAntibodies, MonoclonalAquaporin 4AutoantibodiesMyelin-Oligodendrocyte Glycoprotein

Identifiers

PMID38157878
PMCPMC10756840
OpenAlexW4390431013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.