ArticleOperative neurosurgery (Hagerstown, Md.)2023
Mixed Reality for Cranial Neurosurgical Planning: A Single-Center Applicability Study With the First 107 Subsequent Holograms.
Article in Operative neurosurgery (Hagerstown, Md.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Impact of Mixed Reality on Middle Cerebral Artery Aneurysm Clipping: Initial Experience With 25 Cases.Operative neurosurgery (Hagerstown, Md.) · 2026Article
- Mixed reality applied to surgical planning and tailoring of carotid endarterectomies.Acta neurochirurgica · 2026Article
- PF-CMNet: Progressive Frequency-Aware Cross-Modal Network with Missing-Modality Distillation for 3D Brain Tumor Segmentation.Brain sciences · 2026Article
- From planning to execution: Interactive virtual-reality assisted craniotomy planning in meningioma surgery.Brain & spine · 2026Article
- Microsurgical resection of olfactory groove meningioma via the pterional transsylvian approach with preservation of the bilateral olfactory nerves.Neurosurgical focus: Video · 2026Article
- Comprehensive protocol for mixed reality visualization and navigation using 3D Slicer.PloS one · 2026Article
- Intraoperative use of mixed reality (MR) in humans across surgical disciplines: a major review.3D printing in medicine · 2025Article
- Transforming Global Neurosurgical Education Through Mixed Reality Development: A 12-Year Bibliometric Analysis.Cureus · 2025Review
- Role of mixed reality in the workflow of complex neurooncological surgeries: a case analysis in thalamic surgery.Acta neurochirurgica · 2025Article
- Envisioning the Future of the Neurosurgical Operating Room with the Concept of the Medical Metaverse.Journal of Korean Neurosurgical Society · 2025Article
- Artificial Intelligence and Augmented Reality in Vascular Neurosurgery.Acta neurochirurgica. Supplement · 2025Article
- Integrating Standardized Patient into Case-Based Learning in Posterior Fossa Meningioma Teaching: Evaluating the Added Value Beyond Case-Based Learning Alone.Advances in medical education and practice · 2025Article
- Case Report: Clinical awareness about the effect of laser interstitial thermal therapy on pediatric high-grade brain tumors after radiotherapy.Frontiers in surgery · 2024Article
- A Novel Registration Method for a Mixed Reality Navigation System Based on a Laser Crosshair Simulator: A Technical Note.Bioengineering (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
BACKGROUND AND
objectivesMixed reality (MxR) benefits neurosurgery by improving anatomic visualization, surgical planning and training. We aim to validate the usability of a dedicated certified system for this purpose.
methodsAll cases prepared with MxR in our center in 2022 were prospectively collected. Holographic rendering was achieved using an incorporated fully automatic algorithm in the MxR application, combined with contrast-based semiautomatic rendering and/or manual segmentation where necessary. Hologram segmentation times were documented. Visualization during surgical preparation (defined as the interval between finalized anesthesiological induction and sterile draping) was performed using MxR glasses and direct streaming to a side screen. Surgical preparation times were compared with a matched historical cohort of 2021. Modifications of the surgical approach after 3-dimensional (3D) visualization were noted. Usability was assessed by evaluating 7 neurosurgeons with more than 3 months of experience with the system using a Usefulness, Satisfaction and Ease of use (USE) questionnaire.
resultsOne hundred-seven neurosurgical cases prepared with a 3D hologram were collected. Surgical indications were oncologic (63/107, 59%), cerebrovascular (27/107, 25%), and carotid endarterectomy (17/107, 16%). Mean hologram segmentation time was 39.4 ± 20.4 minutes. Average surgical preparation time was 48.0 ± 17.3 minutes for MxR cases vs 52 ± 17 minutes in the matched 2021 cohort without MxR (mean difference 4, 95% CI 1.7527-9.7527). Based on the 3D hologram, the surgical approach was modified in 3 cases. Good usability was found by 57% of the users.
conclusionThe perioperative use of 3D holograms improved direct anatomic visualization while not significantly increasing intraoperative surgical preparation time. Usability of the system was adequate. Further technological development is necessary to improve the automatic algorithms and reduce the preparation time by circumventing manual and semiautomatic segmentation. Future studies should focus on quantifying the potential benefits in teaching, training, and the impact on surgical and functional outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.