Evidence map›Paper›PMID 38156707›Full record

SynthesisInternational wound journal2024

Utility of dexmedetomidine on surgical site wound pain undergoing thoracoscopic surgery: A meta-analysis.

Mingzhu Li, Kaitian Zhang, Huanqian Lu, Yuqiong Liang, Yuling Zhang, Guifeng Feng

RetractedOpen access · goldAbstract readMeta-AnalysisRetracted Publication
In one paragraph

Synthesis in International wound journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mingzhu LiDepartment of Pharmacy, Gaozhou People's Hospital, Gaozhou, Guangdong, China.
Kaitian ZhangDepartment of Cardiovascular Surgery, Gaozhou People's Hospital, Gaozhou, Guangdong, China.
Huanqian LuDepartment of Pharmacy, Gaozhou People's Hospital, Gaozhou, Guangdong, China.
Yuqiong LiangDepartment of Pharmacy, Gaozhou People's Hospital, Gaozhou, Guangdong, China.
Yuling ZhangDepartment of Pharmacy, Gaozhou People's Hospital, Gaozhou, Guangdong, China.
Guifeng FengDepartment of Pharmacy, Gaozhou People's Hospital, Gaozhou, Guangdong, China.
Gaozhou People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We conducted this study aimed to evaluate the analgesic effect of dexmedetomidine in thoracoscopic surgery on postoperative wound pain, and to provide a reference for clinical use of the drug. We searched PubMed, Embase, Cochrane Library, Web of Science, Wanfang, Chinese Biomedical Literature Database and China National Knowledge Infrastructure databases, and supplemented with manual searching. We searched from database inception to October 2023, to collect the randomised controlled trials (RCTs) on dexmedetomidine application in thoracoscopic surgery. Two researchers screened all the literature according to the inclusion and exclusion criteria and the literature included in the study was evaluated for quality, extracted information and required data. Stata 17.0 software was employed for data analysis and the outcomes were 2 6, 12, 24 and 48 h postoperative wound visual analog scores (VAS). Twenty-four RCTs totalling 2246 patients undergoing thoracoscopic surgery were finally included. The analysis revealed dexmedetomidine applied to thoracoscopic surgery significantly reduced the postoperative wound VAS scores at 2 h (SMD: -0.96, 95% CI: -1.57 to -0.36, p = 0.002), 6 h (SMD: -0.98, 95% CI: -1.27 to -0.69, p < 0.001), 12 h (SMD: -1.19, 95% CI: -1.44 to -0.94, p < 0.001), 24 h (SMD: -0.91, 95% CI: -1.16 to -0.66, p < 0.001) and 48 h (SMD: -0.75, 95% CI: -1.02 to -0.48, p < 0.001). Our results suggest dexmedetomidine applied to thoracoscopic surgery can significantly reduce postoperative wound pain, which is worthy of clinical application.

Indexed as

Analgesics, Non-NarcoticDexmedetomidinePostoperative PainThoracoscopyAdultAgedFemaleHumansMaleMiddle AgedPain MeasurementRandomized Controlled Trials as TopicSurgical WoundAnalgesics, Non-NarcoticDexmedetomidinedexmedetomidinemeta‐analysisthoracoscopic surgerywound pain

Identifiers

PMID38156707
PMCPMC10961883
OpenAlexW4390395458

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.