ArticleJournal of the American Heart Association2024
Transcatheter Closure or Surgery for Symptomatic Paravalvular Leaks: The Multicenter KISS Registry.
Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Amplatzer-Based Transcatheter Paravalvular Leak Closure: A Narrative Review of Device Design, Procedural Strategy, Safety, and Outcomes.Life (Basel, Switzerland) · 2026Review
- Secure the Plug: Ultimate Structural and Intervention Complex Paravalvular Leak Closure and Simultaneous Left Atrial Appendage Closure - A Case Report.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Article
- Pathophysiology, diagnosis, and management of hemolysis in patients with prosthetic valve related paravalvular leaks.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2026Review
- Management of massive paravalvular leak (PVL): a case report of transcatheter mitral paravalvular leak closure.Journal of cardiothoracic surgery · 2026Article
- Multiple Mitral Paravalvular Leak Closure With VSD Occluder in a High Surgical Risk Patient.JACC. Case reports · 2026Article
- Case Report: Transcatheter closure of paravalvular leak following left ventricular assist device and aortic valve replacement.Frontiers in cardiovascular medicine · 2026Article
- Echocardiography-Guided Percutaneous Paravalvular Mitral Leak Closure Without Fluoroscopy.JACC. Case reports · 2025Article
- Left Main Obstruction From Paravalvular Leak Closure Device in Patient With Surgical Aortic Valve Replacement.JACC. Case reports · 2025Article
- Extended reality in cardiovascular care: a systematic review.European heart journal. Digital health · 2025Review
- Transcatheter closure of a large bioprosthetic tricuspid paravalvular leak.Journal of cardiology cases · 2025Article
- Transcatheter or surgical treatment of paravalvular leaks: A meta-analysis of 13 studies and 2003 patients.International journal of cardiology. Heart & vasculature · 2025Review
- Transcatheter closure of paravalvular leak after Bentall surgery in a Marfan patient: a rare case report.Frontiers in cardiovascular medicine · 2025Article
Corrections and comments
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Authors and funding
29 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe optimal treatment of symptomatic paravalvular leak (PVL) remains controversial between transcatheter closure (TC) and surgery. This large-scale study aimed to retrospectively evaluate the long-term outcomes of the patients who underwent reoperation or TC of PVLs. METHODS AND
resultsA total of 335 (men, 209 [62.4%]; mean age, 58.15±12.77 years) patients who underwent treatment of PVL at 3 tertiary centers between January 2002 and December 2021 were included. Echocardiographic features, procedure details, and in-hospital or long-term outcomes were assessed. The primary end point was defined as the all-cause death during follow-up. The regression models were adjusted by applying the inverse probability weighted approach to reduce treatment selection bias. The initial management strategy was TC in 171 (51%) patients and surgery in 164 (49%) cases. Three hundred cases (89.6%) had mitral PVL, and 35 (10.4%) had aortic PVL. The mean left ventricular ejection fraction was 52.03±10.79%. Technical (78.9 versus 76.2%;
conclusionsThe current data suggest that percutaneous closure of PVL was associated with lower early and comparable long-term mortality rates compared with surgery.
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