Evidence map›Paper›PMID 38156458›Full record

ArticleJournal of the American Heart Association2024

Impact of Acute Kidney Injury After Transcatheter Aortic Valve Replacement: A Nationwide Study.

Jeppe Kofoed Petersen, Lauge Østergaard, Nicholas Carlson, Lucas Grove Vejlstrup Bager, Jarl E Strange, Morten Schou, Lars Køber, Emil Loldrup Fosbøl

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
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  8. Transradial vs transfemoral secondary access outcomes in transcatheter aortic valve replacement: an updated systematic review and meta-analysis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Review
  9. Article
  10. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jeppe Kofoed PetersenDepartment of Cardiology Copenhagen University Hospital Rigshospitalet Copenhagen Denmark.ORCID 0000-0002-1166-7877
Lauge ØstergaardDepartment of Cardiology Copenhagen University Hospital Rigshospitalet Copenhagen Denmark.ORCID 0000-0003-3298-1467
Nicholas CarlsonDepartment of Nephrology Copenhagen University Hospital Rigshospitalet Copenhagen Denmark.ORCID 0000-0002-4374-470X
Lucas Grove Vejlstrup BagerDepartment of Cardiology Copenhagen University Hospital Rigshospitalet Copenhagen Denmark.ORCID 0000-0002-9522-1580
Jarl E StrangeDepartment of Cardiology Copenhagen University Hospital Rigshospitalet Copenhagen Denmark.ORCID 0000-0002-1803-5266
Morten SchouDepartment of Cardiology Herlev and Gentofte University Hospital Copenhagen Denmark.ORCID 0000-0002-4271-2466
Lars KøberDepartment of Cardiology Copenhagen University Hospital Rigshospitalet Copenhagen Denmark.ORCID 0000-0002-6635-1466
Emil Loldrup FosbølDepartment of Cardiology Copenhagen University Hospital Rigshospitalet Copenhagen Denmark.ORCID 0000-0002-2048-4167
Copenhagen University Hospital · DKGentofte Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn patients undergoing transcatheter aortic valve replacement (TAVR), the impact of acute kidney injury (AKI) on the prognosis and especially on future kidney function has been sparsely examined, and data from large cohorts are warranted. METHODS AND

resultsWith Danish nationwide registries, we identified all patients undergoing TAVR from 2014 to 2021 with no previous dialysis treatment. According to 2 plasma creatinine samples, we identified those suffering a postprocedural AKI within 21 days after TAVR. With 1 year of follow-up, we compared the associated rates of dialysis treatment and death between patients with and without an AKI using multivariable Cox analysis. Finally, according to the lowest recorded creatinine sample, we assessed the kidney function among AKI survivors between 90 and 180 days after the index date. We identified 4091 TAVRs: 193 (4.7%) with AKI (55.4% men; median age, 82 years) and 3898 (95.3%) without AKI (57.0% men; median age, 81 years). Compared with those without AKI, patients with AKI showed increased associated 1-year rates of dialysis treatment (hazard ratio [HR], 7.20 [95% CI, 4.10-12.66]) and death (HR, 2.39 [95% CI, 1.59-3.58]). After 6 months, 74% of AKI survivors had complete kidney recovery, 14.7% had incomplete kidney recovery, 6.3% failed to recover, and 5.1% were on dialysis treatment.

conclusionsWe identified that AKI after TAVR was associated with an increased rate of future dialysis treatment and all-cause death. Among survivors, 74% had complete kidney recovery within 6 months.

Indexed as

Acute Kidney InjuryAortic Valve StenosisTranscatheter Aortic Valve ReplacementAged, 80 and overAortic ValveCreatinineFemaleHumansMaleRisk FactorsTreatment OutcomeCreatinineacute kidney injuryepidemiologykidney recoverymortalitytranscatheter aortic valve replacement

Identifiers

PMID38156458
PMCPMC10863835
OpenAlexW4390398009

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.