Evidence map›Paper›PMID 38156321›Full record

ArticleFrontiers in cellular and infection microbiology2023

Human vaginal microbiota colonization is regulated by female sex hormones in a mouse model.

Nuzhat Rahman, M Firoz Mian, Aisha Nazli, Charu Kaushic

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. InvestigatingIJID regions · 2026
    Article
  6. Article
  7. Review
  8. Microbiota-dependent IFN-L controls uterine and placental immunity.bioRxiv : the preprint server for biology · 2026
    Article
  9. Inflammatory landscape ofFrontiers in immunology · 2026
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Frontiers in immunology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nuzhat RahmanDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
M Firoz MianDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Aisha NazliDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Charu KaushicDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
McMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Clinically, a Methods: In this study, probiotic, eubiotic, and dysbiotic models were developed in C57BL/6 mice, using probiotic strains Results: Following a single administration, Discussion: Based on the results, we have shown that estrogen played a significant role in the ability for human VMB species to colonize in our mouse models, potentially through a glycogen mediated mechanism. These results suggest there is a dynamic interaction between sex hormones and the VMB, which can affect bacterial diversity and the ability for a VMB to colonize.

Indexed as

Limosilactobacillus reuteriMicrobiotaAnimalsBacteriaDisease Models, AnimalEstradiolFemaleGlycogenHumansLactobacillusMiceMice, Inbred C57BLProgesteroneVaginaEstradiolGlycogenProgesteronebacterial vaginosis (BV)female reproductive healthLactobacillusmouse modelssex hormonesvaginal microbiota (VMB)

Identifiers

PMID38156321
PMCPMC10753781
OpenAlexW4389683477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.